Biotechnology Bulletin ›› 2021, Vol. 37 ›› Issue (5): 174-181.doi: 10.13560/j.cnki.biotech.bull.1985.2020-1079

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Progress on Antiviral Agents Against African Swine Fever Virus

ZHAO Hong-yuan1(), WANG Zhao1, CHENG Wen-yu1(), MA Ning-ning1, LI Man2, WEI Xiao-li2   

  1. 1. School of Modern Agriculture and Biotechnology,Ankang University,Ankang 725000
    2. Animal Husbandry and Veterinary Bureau of Ankang,Ankang 725000
  • Received:2020-08-25 Online:2021-05-26 Published:2021-06-11
  • Contact: CHENG Wen-yu E-mail:zhaohongyuan18@163.com;wenyucheng1989@163.com

Abstract:

African swine fever(ASF),the most serious exotic pig disease,is listed as a class Ⅰ animal disease in China. The continuous infection since the outbreak of ASF in Shenyang on August 2018 is now ravaging the development of China’s pork industry,seriously threating the healthy development of pig breeding. There is no commercialized vaccine or cost-effective antiviral drugs,thus only quick killing is reliable to control the disease once pigs are infected. This review summarized the recent research status of agents including interferons,antibiotics,nucleoside analogues,plant-derived products and other compounds that have been reported to inhibit ASFV replication,aiming to provide theoretical basis and reference for the development of potential anti-ASFV drugs.

Key words: African swine fever virus, antiviral agents, interferons, nucleoside analogues, plant-derived products