Research Progress in Bioactive Natural Products from Lysobacter

doi:10.13560/j.cnki.biotech.bull.1985.2023-0655

Abstract

Abstract:

Microbial secondary metabolites are an important source of natural drugs and are widely used in medical and agricultural production. Actinomycetes and fungi are the main microorganisms that produce antibiotics, but it is becoming increasingly difficult to discover new antibiotics from them after a long and extensive screening. With advances in sequencing technology, more and more microbial genomes are being sequenced, and it has been found that many previously neglected microbes also have the potential to produce new antibiotics. The genus Lysobacter have antagonistic activities against a range of plant pathogenic fungi, bacteria, oomycetes, and nematodes, and several secondary metabolites with novel structures and significant biological activities have been identified from Lysobacter, which have potential applications in biocontrol agents and promising drug leads. In this paper, we review the distribution of Lysobacter resources and their secondary metabolites, aiming to provide a reference for further screening of Lysobacter from the environment and discovering more bioactive natural products.

Key words: Lysobacter, distribution, bioactive natural products

ZHOU Shan-shan HUANG Yuan-long HUANG Jian-zhong LI Shan-ren. Research Progress in Bioactive Natural Products from Lysobacter[J]. Biotechnology Bulletin, 2023, 39(10): 41-49.

Figures/Tables 3

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