Progress on the Secondary Metabolites and Applications of Streptomyces

Abstract

Abstract: Streptomyces widely distributed in the soil as a common microorganisms, researcher had focused much attention on them since they could produce some antibiotics applied in medical and other natural substances, so it has tremendous commercial and medical exploitation value. The research progresses on the kinds of secondary metabolites of Streptomyces isolated from terrestrial and marine habitats as well as extreme environment were reviewed. Meanwhile, The potential applications of the novel metabolites produced by Streptomyces in agriculture, medicine, environmental remediation and other fields in recent years were summarized.

Key words: Streptomyces, Secondary metabolites, Antibiotic, Enzymes

Dai Fangping, Li Shiweng. Progress on the Secondary Metabolites and Applications of Streptomyces[J]. Biotechnology Bulletin, 2014, 0(3): 30-35.

References

[1] Procópio RE, Silva IR, Martins MK, et al. Antibiotics produced by Streptomyces[J]. Braz J Infect Dis, 2012, 16(5):466-471.
[2] Dharmaraj S. Marine Streptomyces as a novel source of bioactive substances[J]. World J Microbiol Biotechnol, 2010, 26(12):2123-2139.
[3] Mohamed SH, Al-Saeedi TA, Sadik AS, et al. Halotolerant streptomycetes isolated from soil at Taif region, Kingdom of Saudi Arabia II:RAPD-PCR analysis and salt tolerance-gene isolation. Afr[J]. J Biotechnol, 2013, 12(13):1452-1458.
[4] Higginbotham SJ, et al. Identification and characterisation of a Strep- tomyces sp. isolate exhibiting activity against methicillin-resistant Staphylococcus aureus[J]. Microbiol Res, 2010, 165(1):82-86.
[5] Cho SS, Choi YH, Simkhada JR, et al. A newly isolated Streptomyces sp. CS392 producing three antimicrobial compounds[J]. Bioproc Biosyst Eng, 2012, 35(1-2):247-254.
[6] Allen AD, Daley P, et al. Characterization of medium chain length(R)-3-hydroxycarboxylic acids produced by Streptomyces sp. JM3 and the evaluation of their antimicrobial properties[J]. World J Microbiol Biotechnol, 2012, 28(9):2791-2800.
[7] Sathiyanarayanan G, Gandhimathi R, Sabarathnam B, et al. Optimiza-tion and production of pyrrolidone antimicrobial agent from marine sponge-associated Streptomyces sp. MAPS15[J]. Bioproc Biosyst Eng, 2013, DOI:10. 1007/s00449-013-1023-2.
[8] Thenmozhi M, et al. Studies on isolation, classification and phyloge-netic characterization of novel antifungal Streptomyces sp. VITSTK7 in India[J]. Curr Res J Bio Sci, 2010, 2(5):306-312.
[9] Ripa FA, Nikkon F, et al. In vitro antibacterial activity of bioactive metabolite and crude extract from a new Streptomyces sp. Streptomyces rajshahiensis[J]. Int J Pharm Tech Res, 2010, 2(1):644-648.
[10] Arasu MV, Duraipandiyan V, Ignacimuthu S. Antibacterial and antifungal activities of polyketide metabolite from marine Streptomyces sp. AP-123 and its cytotoxic effect[J]. Chemosphere, 2013, 90(2):479-487.
[11] Bhave SV, Shanbhag PV, Sonawane SK, et al. Isolation and characterization of halotolerant Streptomycesradiopugnans from Antarctica soil[J]. Appl Microbiol, 2013, 56(5):348-355.
[12] Sadeghi A, Karimi E, Dahaji PA, et al. Plant growth promoting activity of an auxin and siderophore producing isolate of Streptomyces under saline soil conditions[J]. World J Microbiol Biotechnol, 2012, 28(4):1503-1509.
[13] Saurav K, Rajakumar G, Kannabiran K, et al. Larvicidal activity of isolated compound 5-(2, 4-dimethylbenzyl)pyrrolidin-2-one from marine Streptomyces VITSVK5 sp. against Rhipicephalus(Boophilus) microplus, Anopheles stephensi, and Culex tritaeniorh- ynchus[J]. Parasitol Res, 2013, 112(1):215-226.
[14] Arasu MV, Al-Dhabi NA, Saritha V, et al. Antifeedant, larvicidal and growth inhibitory bioactivities of novel polyketide metabolite isolated from Streptomyces sp. AP-123 against Helicoverpa armigera and Spodoptera litura[J]. BMC Microbiol, 2013, 13(105):1-6.
[15] 信艳娟, 艾江宁, 刘亚男, 等. 一株海洋放线菌的分离鉴定及活性研究[J]. 生物技术进展, 2012, 2(5):354-358.
[16] Alvarez-Mico X, Jensen PR, Fenical W, et al. Chlorizidine, a cytotoxic 5H-Pyrrolo isoindol-5-one-containing alkaloid from a marine Streptomyces sp. [J]. Org Lett, 2013, 15(5):988-991.
[17] Meng P, Zhou XX. α-Glucosidase inhibitory effect of a bioactivity guided fraction GIB-638 from Streptomyces fradiae PWH638[J]. Med Chem Res, 2012, 21(12):4422-4429.
[18] Dramae A, Nithithanasilp S, Choowong W, et al. Antimalarial 20-membered macrolides from Streptomyces sp. BCC33756[J]. Tetrahedron, 2013, 69(38):8205-8208.
[19] Chen CX, Song FH, Wang Q, et al. A marine-derived Streptomyces sp. MS449 produces high yield of actinomycin X2 and actinomycin D with potent anti-tuberculosis activity[J]. Appl Microbiol Biotechnol, 2012, 95(4):919-927.
[20] Christhudas IVSN, Kumar PP, Agastian P. In vitro a-Glucosidase inhibition and antioxidative potential of an endophyte species(Streptomyces sp. Loyola UGC)isolated from Datura stramonium L. [J]. Curr Microbiol, 2013, 67(1):69-76.
[21] Eto K, Yoshino M, Takahashi K, et al. Total synthesis of oxazolomycin A[J]. Org Lett, 2011, 13(19):5398-5401.
[22] Elleuch L, Shaaban M, Smaoui S, et al. Bioactive secondary metabo-lites from a new terrestrial Streptomyces sp. TN262[J]. Appl Bio-chem Biotechnol, 2010, 162(2):579-593.
[23] Salamoni SP, Mann MB, Campos FS, et al. Preliminary characteri-zation of some Streptomyces species isolated from a composting pro-cess and their antimicrobia potential[J]. World J Microbiol Biot-echnol, 2010, 26(10):1847-1856.
[24] Cho SS, Choi YH, Simkhada J R, et al. A newly isolated Streptom- yces sp. CS392 producing three antimicrobial compounds[J]. Bioproc Biosyst Eng, 2012, 35(1-2):247-254.
[25] Manivasagan P, Gnanam S, Sivakumar K, et al. Antimicrobial and cytotoxic activities of an actinobacteria(Streptomyces sp. PM-32)isolated from an offshore sediments of the Bay of Bengal in Tamilnadu[J]. Advan Biol Res, 2009, 3(5-6):231-236.
[26] Kishimoto S, Tsunematsu Y, Nishimura S, et al. Tumescenamide C, an antimicrobial cyclic lipodepsipeptide from Streptomyces sp. [J]. Tetrahedron, 2012, 68(27-28):5572-5578.
[27] Singh AK, Chhatpar HS. Purification, characterization and thermodynamics of antifungal protease from Streptomyces sp. A6[J]. J Basic Microbiol, 2011, 51(4):424-432.
[28] Choi HJ, Kim DW, Choi YW, et al. Broad-spectrum in vitro antimi-crobial activities of Streptomyces sp. strain BCNU 1001[J]. Bio-tech and Bioproc Eng, 2012, 17(3):576-583.
[29] Sanchez López JM, Martinez Insua M, Perez Baz J, et al. New cytotoxic indolic metabolites from a marine Streptomyces[J]. J Nat Prod, 2003, 66(6):863-864.
[30] Shin C, Lim H, Moon S, et al. A novel antiproliferative agent, phenylpyridineylbutenol, isolated from Streptomyces sp. [J]. Bioorg Med Chem Lett, 2006, 16(21):5643-5645.
[31] 杨辉, 闫守泉, 赖祯冬, 等. 产溶菌酶白色链霉菌的筛选及鉴定[J]. 现代食品科技, 2011, 27(8):881-884.
[32] Thumar JT, et al. Organic solvent tolerance of an alkaline protease from salt-tolerant alkaliphilic Streptomyces clavuligerus strain Mit-1[J]. J Ind Microbiol Biotechnol, 2009, 36(2):211-218.
[33] Han Y, et al. Characterization of antifungal chitinase from marine Streptomyces sp. DA11 associated with south China sea sponge Cra- niella australiensis[J]. Marine Biotechnol, 2009, 11:132-140.
[34] Bajaj BK, Sharma P. An alkali-thermotolerant extracellular protease from a newly isolated Streptomyces sp. DP2[J]. New Biotechnol, 2011, 28(6):725-732.
[35] Dubey R, Kattusamy K, Dharmalingam K, et al. Daunorubicin forms a specific complex with a secreted serine protease of Streptomyces peucetius[J]. World J Microbiol Biotechnol, 2013, DOI:10. 1007/s11274-013-1442-x.
[36] Mander P, Cho SS, Simkhada JR, et al. A low molecular weight chymotrypsin-like novel fibrinolytic enzyme from Streptomyces sp. CS624[J]. Process Biochem, 2011, 46(7):1449-1455.
[37] Saratale GD, Saratale RG, Oh SE. Production and characterization of multiple cellulolytic enzymes by isolated Streptomyces sp. MDS[J]. Biomass Bioenergy, 2012, 47:302-315.
[38] Li XT, She YL, Sun BG, et al. Purification and characterization of a cellulase-free, thermostable xylanase from Streptomyces rameus L2001 and its biobleaching effect on wheat straw pulp[J]. Biochem Eng J, 2010, 52(1):71-78.
[39] Lu LH, Zeng GM, Fan CZ, et al. Characterization of a laccase-like multicopper oxidase from newly isolated Streptomyces sp. C1 in agricultural waste compost and enzymatic decolorization of azo dyes[J]. Biochem Eng J, 2013, 72:70-76.
[40] Simkhada JR, Cho SS, Mander P, et al. Purification, biochemical properties and antithrombotic effect of a novel Streptomyces[J]. Thrombosis Res, 2012, 129(2):176-182.
[41] Bhasin S, Modi HA. Optimization of fermentation medium for the production of glucose isomerase using Streptomyces sp. SB-P1[J]. Biotechnol Res Int, 2012, DOI:10. 1155/2012/874152.
[42] Fróes A, Macrae A, Rosa J, et al. Selection of a Streptomyces strain able to produce cell wall degrading enzymes and active against scle-rotinia sclerotiorum[J]. Microbiol J, 2012, 50(5):798-806.
[43] Rahulan R, Dhar KS, et al. Characterization of leucine amino pept-idase from Streptomyces gedanensis and its appli-cations for protein hydrolysis[J]. Process Biochem, 2012, 47(2):234-242.
[44] Simkhada JR, Cho SS, Park SJ, et al. An oxidant and organic solvent-resistant alkaline metalloprotease from Streptomyces olivochromo- genes[J]. Appl Biochem Biotechnol, 2010, 162(5):1457-1470.
[45] Lakshmipathy TD, Prasad ASA, Kannabiran K. Production of biosurfactant and heavy metal resistance activity of Streptomyces sp. VITDDK3-a novel halotolerant actinomycetes isolated from saltpan soil[J]. Adv Bio Res, 2010, 4(2):108-115.
[46] 赵辉, 闫华晓, 王霞, 等. 一株产天然蓝色素海洋链霉菌的筛选鉴定[J]. 生物学杂志, 2011, 28(3):63-65.
[47] Itoh T, Kinoshita M, Aoki S , et al . Komodoquinone A, a novel neuri-togenic anthracycline, from marine Streptomyces sp. KS3[J]. J Nat Prod, 2003, 66(10):1373-1377.
[48] Hernandez M, Hernandez-Coronado MJ, Ball AS, et al. Degradation of alkali-lignin residues from solid-state fermentation of wheat straw by streptomycetes[J]. Biodegradation, 2001, 12(4):219-223.
[49] 司美茹, 江翠翠, 等. 一株降解原油链霉菌的分离鉴定与降解特性研究[J]. 生态与农村环境学报, 2010, 26(5):508-512.
[50] Ai HX, Zhou JT, et al. Responses of a novel salt-tolerant Streptom- yces albidoflavus DUT_AHX capable of degrading nitrobenzene to salinity stress[J]. Biodegradation, 2009, 20(1):67-77.