Role of MicroRNAs in Genes Regulatory Apoptosis

Abstract

Abstract: MicroRNA（miRNA）, a class of non-coding small RNA molecules, widely exists in the most of the animals and plants. Major function of MicroRNA is expression regulation of target gene. This regulation is primarily carried out by repression of translation in mammals. Apoptosis is programmed cell death regulated by various genes and the role of miRNAs in apoptosis is not fully understood, however, evidence is mounting that miRNAs are important in this process. In this paper, the relationship between MicroRNA and cell apoptosis, and concludes the possible regulation mechanism were reviewed.

Key words: MicroRNA, Apoptosis, Gene, Signal pathway

Qi Renli, Huang Jinxiu, Yang Feiyun, Liu Zuohua. Role of MicroRNAs in Genes Regulatory Apoptosis[J]. Biotechnology Bulletin, 2014, 0(7): 20-25.

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