Biotechnology Bulletin ›› 2022, Vol. 38 ›› Issue (1): 1-14.doi: 10.13560/j.cnki.biotech.bull.1985.2021-1326

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Research Progress of RNA Editing

ZHU Lin(), XIAN Feng-jun, ZHANG Qian-nan, HU Jun()   

  1. State Key Laboratory of Hybrid Rice,College of Life Sciences,Wuhan University,Wuhan 430072
  • Received:2021-10-21 Online:2022-01-26 Published:2022-02-22
  • Contact: HU Jun E-mail:linzhu@whu.edu.cn;junhu@whu.edu.cn

Abstract:

RNA editing is a post-transcriptional process on the target transcripts by base insertion,deletion,or replacement. This important epigenetic phenomenon is also considered as a correction mechanism for genetic restoration at the RNA level. Here,we reviewed the RNA editing systems based on PPR gene family in plants and CRISPR/Cas editing system in animal, introduced the important role of RNA editing in the plant growth and development, and prospected future application of RNA editing. In addition we also summarized the recent research on RNA editing database,which support the follow-up research of RNA editing.

Key words: RNA editing, organelles, PPR protein, RNA editosomes, CRISPR/Cas