Review on Research Progresses in the Fermentation Methods to Produce Glucosamine

Abstract

Abstract: Glucosamine(GlcN)is an important hexosamine. It is formed by one hydroxyl group of glucose substituted by amino and has an effective role in the treatment of rheumatoid arthritis in the cartilage tissue. Besides, it is regarded as the natural harmless ingredients for food and health products. Currently, the methods for the production of GlcN include acid hydrolysis, enzymatic hydrolysis and microbial fermentation. For acid hydrolysis and enzymatic hydrolysis to product GlcN can lead to some adverse effects, such as environmental pollution, microbial fermentation is getting more attention from researchers. This overview focused on the biosynthetic pathway of microbial metabolism, microbial production of GlcN, and the direction of research for GlcN fermentation.

Key words: Glucosamine, Biosynthetic pathway, Microbial fermentation

Wang Sheng, Li Piwu, Liu Dianlei, Li Yiming, Lin Jingjing. Review on Research Progresses in the Fermentation Methods to Produce Glucosamine[J]. Biotechnology Bulletin, 2014, 0(1): 68-74.

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