The Biosynthesis and Metabolic Engineering of Very Long-chain Monounsaturated Fatty Acid

doi:10.13560/j.cnki.biotech.bull.1985.2015.12.006

Abstract

Abstract: Very long-chain monounsaturated fatty acids(VLCMFA)are fatty acids with aliphatic tail of≥ 20 carbons and a sole unsaturated double bond. VLCMFA has been discovered in a variety of plants and a few of microalgae. Up to now, four VLCMFAs have been identified, they are gadoleic acid(C20:1), erucic acid(C22:1), nervonic acid(C24:1), and ximenic acid(C26:1). VLCMFA shows great potentials in pharmaceutical and chemical industries. This review focuses on the research progress on biosynthesis and metabolic engineering of VLCMFA, which aims at providing the reference for its applications.

Key words: fatty acid, very long-chain monounsaturated fatty acid, erucic acid, nervonic acid, metabolic engineering

Tian Deyu, Wang Shian, Wang Lihao, Wang Jialin, Li Fuli. The Biosynthesis and Metabolic Engineering of Very Long-chain Monounsaturated Fatty Acid[J]. Biotechnology Bulletin, 2015, 31(12): 42-49.

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