Recent Advances in Plant Pep Peptide

doi:10.13560/j.cnki.biotech.bull.1985.2021-0025

Abstract

Abstract:

Plants harness many endogenous signal molecules,including hormones and polypeptides,to orchestrate developmental processes and responses to various environmental stresses. Peps are a class of 20-30 amino acid-long polypeptides that are widely distributed among angiosperms plant species. Peps can be perceived by plasma membrane-associated PEPR receptors and play important roles in multiple aspects of plant growth and defense. It has been reported that Peps are critical for plant defense against biological stresses such as pathogen infection and insect biting,as well as for plant tolerance to abiotic stresses such as high salinity. Moreover,Peps have also been shown to regulate the plant growth and development such as root elongation and leaf senescence. Here,we review recent advances in the generation of Peps,perception of receptor,signal transduction and other biological functions. We also discuss and prospect important unsolved scientific issues in Pep signaling and its potential applications in practice,aiming to provide reference for researchers in this field.

Key words: Pep, PEPR, small peptide, signaling transduction

NIE Jia-yue, YANG Wen-wen, FAN Hong-xia, WANG You-ping, WU De-wei. Recent Advances in Plant Pep Peptide[J]. Biotechnology Bulletin, 2021, 37(9): 219-225.

Figures/Tables 3

Fig.1 Amino acid sequence conservation analysis of Pep precursor proteins PROPEP1-PROPEP8 from Arabidopsis thaliana The black underlines mark the position of mature Pep sequence after processing,the red underline marks the position of the SSG-x2-G-x2-N motif

Fig.2 Amino acid sequence conservation analysis of Pep1-Pep8 from Arabidopsis thaliana

Fig.3 Pep-PEPR signal transduction and the mechanisms underlying their regulation of plant growth,development and defense The precursor protein PROPEPs are cleaved by CM4 at appropriate Ca2 + concentration to release mature Peps,and this process is regulated by a positive feedback of Pep signaling pathway. The mature Peps are perceived by the receptor PEPRs,which enables PEPRs to form heterodimer with their co-receptor BAK1 and transduce the signal to cytoplasmic receptor kinase BIK1,thereby activating various downstream signal pathways,such as JA,ET,Auxin and ROS,to regulate plant growth and development,as well as plant defense responses

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