Abstract: Bacterial disease is the most common disease which caused high mortality in aquaculture, people have pay more attention to the identification of pathogens. As the microbial ribosomal RNA（rRNA）database is getting more sophisticated, rRNA analysid has been widely recognized as the main basis for classification of bacteria, rRNA become a powerful tool for identification of pathogen. In this paper, we reviewed the character, research method and the application of rRNA gene in detection of aquatic anmiml’s pathogenic bacteria, and analysised the existing problems in the application.

Key words: rRNA, Gene, Aquaculture, Pathogenic bacterium identification