Anti-aging Effect and Molecular Mechanism of Probiotics：A Review

doi:10.13560/j.cnki.biotech.bull.1985.2019-0635

Abstract

Abstract: Aging can cause many adverse physiological changes in individuals and increase their susceptibility to disease. Clasrifying the mechanism of aging is crucial for seeking intervention approaches. Current research findings suggest that free radical oxidative stress,inflammatory aging,immune aging,and intestinal flora imbalance are the main mechanisms of aging. Besides,probiotics have been reported to have potential anti-aging effects. This paper compares and analyzes the anti-aging evaluation models of probiotics,and focuses on the effects of probiotics on senescence-induced alterations of intestinal flora and anti-aging related signaling pathways,thus providing new ideas for further studying the anti-aging effect of probiotics.

Key words: probiotics, anti-aging, evaluation model

YU Jie, LIU Xin, ZHANG Chi, ZHAO Ji-chun, LI Fu-hua, MING Jian. Anti-aging Effect and Molecular Mechanism of Probiotics：A Review[J]. Biotechnology Bulletin, 2020, 36(1): 167-174.

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