生物技术通报 ›› 2017, Vol. 33 ›› Issue (9): 23-31.doi: 10.13560/j.cnki.biotech.bull.1985.2017-0290

• 综述与专论 • 上一篇    下一篇

鱼类基因组研究进展

徐钢春1,2,杜富宽2,卞超3,石琼3,徐跑1,2   

  1. 1. 南京农业大学无锡渔业学院,无锡 214081;
    2.中国水产科学研究院淡水渔业研究中心 农业部淡水渔业和种质资源利用重点实验室,无锡 214081;
    3. 深圳市华大海洋研究院 深圳华大基因研究院,深圳 518083
  • 收稿日期:2017-04-03 出版日期:2017-09-01 发布日期:2017-09-15
  • 作者简介:徐钢春,男,副研究员;研究方向:鱼类繁育分子生物学;E-mail: xugc@ffrc.cn
  • 基金资助:
    国家自然科学基金面上项目(31672643),江苏省水产三新工程重大专项(D2015-14),江苏省科技成果转化专项(BA2015167)

Research Progress on Fish Genomics

XU Gang-chun1,2,DU Fu-kuan2,BIAN Chao3,SHI Qiong3,XU Pao1,2   

  1. 1. Wuxi Fisheries College,Nanjing Agricultural University,Wuxi 214081;
    2. Key Laboratory of Freshwater Fisheries and Germplasm Resources Utilization,Ministry of Agriculture,Freshwater Fisheries Research Center,Chinese Academy of Fishery Sciences,Wuxi 214081;
    3. BGI Shenzhen Academy of Marine Sciences,BGI,Shenzhen 518083
  • Received:2017-04-03 Published:2017-09-01 Online:2017-09-15
  • Supported by:
    参 考 文 献

摘要: 鱼类基因组研究利用大规模测序获取有关物种的基因组序列信息,进而阐明鱼类生物学特性、表型变异与基因组结构之间的关系,在鱼类的种质鉴定、遗传育种、动物营养、环境毒理和病害防治等领域具有巨大的应用潜力。自2001年首先对斑马鱼的基因组测序起,到目前为止已有近40个鱼类物种的全基因组测序完成,且其相关的生物学特征、遗传进化规律等得到较全面的解析。将从鱼类全基因组测序技术发展历程和鱼类基因组解析两大部分对鱼类基因组研究进展进行综述,旨在进一步了解鱼类基因组的研究现状、发展趋势和应用前景,为后续鱼类基因组研究提供参考。

关键词: 鱼类, 基因组, 基因组学

Abstract: Fish genome sequencing is utilized for searching the genomics sequence information,subsequently clarifying the fish biological characteristics,and the relationship between the phenotypic variation and genome structures.. It has great applicable potential in fish research and economic fields,such as germplasm identification,genetic breeding,animal nutrition,environmental toxicology,disease control,and so on. Since the first report of zebrafish genome sequencing in 2001,nearly 40 fish genomes have been sequenced and published,which also illuminated their related biological characteristics and provided comprehensive interpretation of genetic evolution with high-yield and low-cost development of the genome sequencing technologies. The main aim of this review is to summarize research progress on the whole genome sequencing technology and the deep data analyses of fish genomes,and to further understand the recent development of fish genome researches and application prospects,so as to provide comprehensive references for subsequent fish genome researches.

Key words: fish, genome, genomics