拟南芥花分生组织决定基因AGL24对花发育的影响

摘要/Abstract

摘要： AGAMOUS-LIKE 24(AGL24)基因编码MADS蛋白，在植物花发育的不同时期发挥着重要的作用。综述了AGL24如何通过和其他花分生组织决定基因的相互作用来影响拟南芥花的发育，调节开花时间，这将有助于人们对开花基因调控网络有更进一步的认识，能够在生产上有效的调控开花时间，从而为植物育种提供借鉴。

关键词: 拟南芥, AGL24, 花发育

Abstract: AGAMOUS-LIKE24(AGL24)encodes a typical MADS-domain protein that plays a very important role at different stages of flower development. This paper reviews how AGL24 interacts with other floral meristem identity genes to affect flower development of Arabidopsis thaliana, then regulate flowering time, which will help us to have a better understanding of flowering gene regulatory network and to regulate effectively the flowering time in production. It can provide reference for plant breeding.

Key words: Arabidopsis thaliana, AGL24, Flower development

江为, 谷慧英, 王志敏, 宋明, 汤青林. 拟南芥花分生组织决定基因AGL24对花发育的影响[J]. 生物技术通报, 2014, 0(4): 6-13.

Jiang Wei, Gu Huiying, Wang Zhimin, Song Ming, Tang Qinglin. The Flower Development of Arabidopsis thaliana Affected by Floral Meristem Identity Gene AGL24[J]. Biotechnology Bulletin, 2014, 0(4): 6-13.

参考文献

[1] Koornneef M, Alonso-Blanco C, Peeters AJM, et al. Genetic control of flowering time in Arabidopsis[J]. Ann Rev Plant Physiol, Plant Mol Biol, 1998, 49：345-370.
[2] Simpson GG, Dean C. Arabidopsis, the Rosetta stone of flowering time?[J]. Science, 2002, 296：285-289.
[3] Mouradov A, Cremer F, Coupland G. Control of flowering time：interacting pathways as a basis for diversity[J]. Plant Cell, 2002, 14：S111-S130.
[4] Koornneef M, Alonso-Blanco C, Blankestijn-de Vries H, et al. Genetic interactions among late-flowering mutants of Arabidopsis[J]. Genetics, 1998, 148：885-892.
[5] Levy YY, Dean C. The transition to flowering[J]. Plant Cell, 1998, 10：1973-1989.
[6] Hartmann U, Ho-hmann S, Nettesheim K, et al. Molecular cloning of SVP：a negative regulator of the floral transition in Arabidopsis[J]. Plant J, 2000, 21：351-360.
[7] Yu H, Xu Y, Tan EL, et al. AGAMOUS-LIKE 24, a dosage-dependent mediator of the flowering signals[J]. Proc Natl Acad Sci USA, 2002, 99：16336-16341.
[8] Michaels SD, Ditta G, Gustafson-Brown C, et al. AGL24 acts as a promoter of flowering in Arabidopsis and is positively regulated by vernalization[J]. Plant J, 2003, 33：867-874.
[9] Gregis V, Sessa A, Colombo L, et al. AGAMOUS-LIKE24 and SHORT VEGETATIVE PHASE determine floral meristem identity in Arabidopsis[J]. Plant J, 2008, 56：891-902.
[10] Elena RA, Mariana B, Adriana C, et al. Flower development［M]. The Arabidopsis Book, 2010.
[11] Masiero S, Li MA, Will I, et al. INCOMPOSITA：a MADS-box gene controlling prophyll development and floral meristem identity in Antirrhinum[J]. Development, 2004, 131：5981-5990.
[12] Liu C, Zhou J, Bracha-Drori K, et al. Specification of Arabidopsis floral meristem identity by repression of floweringtime genes[J]. Development, 2007, 134：1901-1910.
[13] Yu H, Ito T, Wellmer F, et al. Repression of AGAMOUS-LIKE 24 is a crucial step in promoting flower development[J]. Nat Genet, 2004 36：157-161.
[14] Gregis V, Sessa A, Colombo L, et al. AGL24, SHORT VEGETAT-IVE PHASE, and APETALA1 redundantly control AGAMOUS dur-ing early stages of flower development in Arabidopsis[J]. Plant Cell, 2006, 18：1373-1382.
[15] Ramamoorthy R, Phua EE, Lim S, et al. Identification and characte-rization of RcMADS1, an AGL24 Ortholog from the Holoparasitic Plant Rafflesia cantleyi Solms-Laubach(Rafflesiaceae)[J]. PLOS ONE, DOI：10.1371/journal.done.0067243.
[16] Kardailsky I, Shukla VK, Ahn JH, et al. Activation tagging of the floral inducer FT[J]. Science, 1999, 286(5446)：1962-1965.
[17] Kobayashi Y, Kaya H, Goto K, et al. A pair of related genes with antagonistic roles in mediating flowering signals[J]. Science, 1999, 286(5446)：1960-1962.
[18] Li D, Liu C, Shen L, et al. A repressor complex governs the integration of flowering signals in Arabidopsis[J]. Dev Cell, 2008, 15：110-120.
[19] Lee JH, Yoo SJ, Park SH, et al. Role of SVP in the control of flowering time by ambient temperature in Arabidopsis[J].Genes Dev, 2007, 21(4)：397-402.
[20] Yoo SK, Chung KS, Kim J, et al. Constans activates suppressor of overexpression of constans 1 through Flowering Locus T to promote flowering in Arabidopsis[J]. Plant Physiol, 2005, 139：770-778.
[21] Searle I, He Y, Turck F, et al. The transcription factor FLC confers a flowering response to vernalization by repressing meristem competence and systemic signaling in Arabidopsis[J]. Genes Dev, 2006, 20：898-912.
[22] Liu C, Chen H, Er HL, et al. Direct interaction of AGL24 and SOC1 integrates flowering signals in Arabidopsis[J]. Development, 2008, 135：1481-1491.
[23] Samach A, Onouchi H, Gold SE, et al. Distinct roles of CONSTANS target genes in reproductive development of Arabidopsis[J]. Science, 2000, 288(5471)：1613-1616.
[24] Corbesier L, Vincent C, Jang S, et al. FT protein movement contributes to long-distance signaling in floral induction of Arabidopsis[J]. Science, 2007, 316：1030-1033.
[25] Hepworth SR, Valverde F, Ravenscroft D, et al. Antagonistic regulation of flowering-time gene SOC1 by CONSTANS and FLC via separate promoter motifs[J]. EMBO J, 2002, 21：4327-4337.
[26] Lee H, Suh SS, Park E, et al. The AGAMOUS-LIKE 20 MADS domain protein integrates floral inductive pathways in Arabidopsis[J]. Genes Dev, 2000, 14：2366-2376.
[27] Bowman JL, Alvarez J, Weigel D, et al. Control of flower development in Arabidopsis thaliana by APETALA1 and interacting genes[J]. Development, 1993, 119：721-743.
[28] Kempin SA, Savidge B, Yanofsky MF. Molecular basis of the cauliflower phenotype in Arabidopsis[J]. Science, 1995, 267：522-525.
[29] Chang L, Zhi WNT, Yang B, et al. A conserved genetic pathway determines inflorescence architecture in Arabidopsis and rice[J]. Dev Cell, 2013, 24：612-622.
[30] Mandel MA, Gustafson-Brown C, Savidge B, et al. Molecular characterization of the Arabidopsis floral homeotic gene APETALA1[J]. Nature, 1992, 360：273-277.
[31] Ratcliffe OJ, Bradley DJ, Coen ES. Separation of shoot and floral identity in Arabidopsis[J]. Development, 1999, 126：1109-1120.
[32] Folter S, Immink RG, Kieffer M, et al. Comprehensive interaction map of the Arabidopsis MADS Box transcription factors[J]. Plant Cell, 2005, 17：1424-1433.
[33] Wellmer F, Alves-Ferreira M, Dubois A, et al. Genome-wide analysis of gene expression during early Arabidopsis flower development[J]. PLoS Genet, 2006, 2：e117.
[34] Kaufmann K, Wellmer F, Muino JM, et al. Orchestration of floral initiation by APETALA1[J]. Science, 2010, 328：85-89.
[35] Gregis V, Sessa A, Dorca-Fornell C, et al. The Arabidopsis floral meristem identity genes AP1, AGL2 and SVP directly repress class B and C floral homeotic genes[J]. Plant J, 2009, 60：626-637.
[36] Liu C, Xi W, Shen L, et al. Regulation of floral patterning by flowering time genes[J]. Dev Cell, 2009, 5：711-722.
[37] Sieburth LE, Meyerowitz EM. Molecular dissection of the AGAMOUS control region shows that cis elements for spatial regulation are located intragenically[J]. Plant Cell, 1997, 9：355-365.
[38] Bomblies K, Dagenais N, Weigel D. Redundant enhancers mediate transcriptional repression of AGAMOUS by APETALA2[J]. Dev Biol, 1999, 216：260-264.
[39] Deyholos MK, Sieburth LE. Separable whorl-specific expression and negative regulation by enhancer elements within the AGAMOUS second intron[J]. Plant Cell, 2000, 12：1799-1810.
[40] Lohmann JU, Hong R, Hobe M, et al. A molecular link between stem cell regulation and floral patterning in Arabidopsis[J]. Cell, 2001, 105：793-803.
[41] Bao X, Franks RG, Levin JZ, et al. Repression of AGAMOUS by BELLRINGER in floral and inflorescence meristems[J]. Plant Cell, 2004, 16：1478-1489.
[42] Hong RL, Hamaguchi L, Busch MA, et al. Regulatory elements of the floral homeotic gene AGAMOUS identified by phylogenetic footprinting and shadowing[J]. Plant Cell, 2003, 15：1296-1309.
[43] Riechmann JL, Meyerowitz EM. Determination of floral organ identity by Arabidopsis MADS domain homeotic proteins AP1, AP3, PI, and AG is independent of their DNA-binding specificity[J]. Mol Biol Cell, 1997, 8：1243-1259.
[44] Cho RJ, Fromont-Racine M, Wodicka L, et al. Parallel analysis of genetic selections using whole genome oligonucleotide arrays[J]. Proc Natl Acad Sci USA, 1998, 95：3752-3757.
[45] Immink RG, Tonaco IA, Shchennikova A, et al. SEPALLATA3：the ‘glue’ for MADS box transcription factor complex formation[J]. Genome Biol, 2009, 10：R24.
[46] Smaczniak C, Immink RG, Muino JM, et al. Characterization of MADS-domain transcription factor complexes in Arabidopsis flower development[J]. Proc Natl Acad Sci USA, 2012, 109：1560-1565.
[47] Ditta G, Pinyopich A, Robles P, et al. The SEP4 gene of Arabidopsis thaliana functions in floral organ and meristem identity[J]. Curr Biol, 2004, 14：1935-1940.