便携式生物光学传感器的研究进展

doi:10.13560/j.cnki.biotech.bull.1985.2020-1041

摘要/Abstract

摘要：

生物光学传感器是一种对生物物质敏感并将其浓度转换为光信号,再由光电器件转换成电信号进行检测的仪器。由于随着微加工技术和纳米技术的进步,生物光学传感器将不断的微型化,各种便携式生物光学传感器的出现使得人们在家中进行疾病诊断、在市场上直接检测食品及在野外快速检测环境污染成为可能。便携式生物光学传感器一般由光源、光学通路和光电元件三部分组成。传感器结构中各个组件的优化处理将有利于检测设备在实际运用中的便利性和在复杂环境中的适用性,同时也有利于提高生物检测的灵敏度。主要从激励光源的选择、生物光学检测的原理、用于传感光源分析的半导体光敏元件3方面,描述近年来常见的便携式生物光学传感器的研究进展。未来生物检测器件将趋于成本低廉、便携快捷、智能高效等特点,基于生物光学反应特性的研究和传感器结构制备的优化将使得便携式生物光学传感器在未来传感检测应用中具有巨大的商业价值和广泛的实用价值。

关键词: 生物光学传感器, 微加工技术, 纳米技术, 便携式, 快速检测, 半导体光敏元件

Abstract:

A bio-optical sensor is an instrument that is sensitive to biological substances and converts its concentration information into optical signal,which is then converted into electrical signal by a photoelectric device for detection. With the improvement of micro manufacturing technology and nanoscience,bio-optical sensors would constantly be miniaturized. The emergence of various portable bio-optical sensors has made these feasible：diagnosis being carried out at home,food quality being tested on market and environmental pollution being rapidly detected in field. A portable bio-optical sensor is generally composed of three parts,i.e. a light source,an optical path and a photoelectric element. The optimization of the components in the sensor system would be beneficial to convenient detection and flexible applicability,as well as the enhancement of the sensitivity. This paper focuses on the research progress on portable bio-optical sensors from 3 aspects of the excitation light source,the principle of bio-optical detection,and the semiconductor photosensitive elements respectively. In the future,biological detection devices are tending to be low-cost,portable,intelligent and efficient. The research based on bio-optical characteristics and the optimization of sensor structure is expected to allow portable bio-optical sensors to have great commercial value and broad application value in future sensing detection.

Key words: bio-optical sensor, micro manufacturing technology, nanoscience, portable, rapid detection, semiconductor photoelectric device

付志强, 熊艳. 便携式生物光学传感器的研究进展[J]. 生物技术通报, 2021, 37(3): 219-226.

FU Zhi-qiang, XIONG Yan. Research Progress on Portable Bio-optical Sensors[J]. Biotechnology Bulletin, 2021, 37(3): 219-226.

图/表 2

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