Research Advance of RNAi in Anti-influenza Virus

doi:10.13560/j.cnki.biotech.bull.1985.2014.12.009

Abstract

Abstract: The RNAi technology has been widely used in drug and vaccine development of the prevention and treatment of various kinds of human diseases pathogeny,and has made great achievements.Antigenic drift and antigenic shift extremely easily occurred in influenza virus, which had put forward a bigchallenge for the development of anti-influenza virus drugs and vaccines.The appearance of RNAi technology gived good ideas for the prevention and control of influenza.This paper summarized the research status and prospects of using RNAi technology to develop anti-influenza virus drugs and new influenza vaccine at home and abroad in recent years, in order to provide references for the research for the prevention and control of influenza.

Key words: Influenza virus, RNA interference, siRNA, miRNA, Replication, Vaccine

Han Qinggong, Zheng Yushu. Research Advance of RNAi in Anti-influenza Virus[J]. Biotechnology Bulletin, 2014, 0(12): 55-60.

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