Abstract: Cucumber mosaic virus（CMV）is the type member of single stranded RNA viruses. As it infects wide host species and induces serious symptoms,it has been considered as one of the most impact plant virus and also the severe plant disease in the world. Many domestic and overseas scholars have investigated extensively about the CMV genes,gene-encoded products and plant-virus interactions since it was reported in 1916. With the development of high-throughput sequencing technology and proteomic technology,the molecular mechanism of viral virulence has been made great progresses. In this review,we introduce the role of viral encoding proteins,its associated satellite RNA and host factors that are involved in the development of symptoms,and also discusse the further study on viral virulence of CMV,which will provide a useful reference for CMVrelated studies.

Key words: cucumber mosaic virus, pathogenic mechanism, small interfering RNA, protein-protein interaction