Research Progress on Fibroblast Growth Factor 5

doi:10.13560/j.cnki.biotech.bull.1985.2018-0622

Abstract

Abstract: FGF5（fibroblast growth factor 5，FGF5）is a member of fibroblast growth factors（FGFs），which possesses a variety of biological functions. Previous studies have found that FGF5 plays an important role in the cyclical growth of mammalian hair and is a key signal molecule from anagen to catagen. FGF5 also involves in animal limb development，human glioblastoma multiforme，melanoma，hepatocellular carcinoma and hypertension. In this paper，we review the biological functions of FGF5 and the related research results in disease formation in recent years，aiming at providing theoretical basis for its further research and rational utilization in the fields of human hair growth，animal villus resources utilization，limb development，and tumor diagnosis and treatment.

Key words: FGF5, hair growth, limb development, tumor, hypertension

LEI Lei BAO, Peng-jia, LIANG Chun-nian, CHU Min, YAN Ping. Research Progress on Fibroblast Growth Factor 5[J]. Biotechnology Bulletin, 2019, 35(3): 144-150.

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