Research Progress on Biotransformation Modification of Anthocyanins

doi:10.13560/j.cnki.biotech.bull.1985.2019-0262

Abstract

Abstract: Anthocyanins,as a natural water-soluble food coloring,possess a variety of important physiological functions and biological activities as well as high medicinal and health care value,and thus demonstrate great commercial potential. Anthocyanins are formed by the condensation reaction of anthocyanidin and saccharides in glycosidic bonds. The mother nucleus of the anthocyanin is 2-phenylbenzopyryalium cationic aglycone,and there are multiple active hydroxyl groups in the structure,which have poor stability and are sensitive to pH value,light,temperature and other factors,and easily leading to the loss of color or activity. In addition,anthocyanin is strongly hydrophilic and poor soluble in hydrophobic environment,thus it is not easy to pass through the phospholipid bilayer biofilm,resulting in a low bioavailability. Therefore,anthocyanin ester derivatives with improved physical and chemical properties and enhanced stability and good bioavailability may be obtained via acylation modification of anthocyanins on the basis of maintaining the original basic structure,which is an important approach to solve the problem in applying anthocyanins and also a hot and difficult topic in the current research. At present,biological acylation modification of anthocyanins mainly includes plant cell transformation,enzymatic transformation and whole cell microbial transformation. In this paper,the stability,bioactivity and acylation modification with biotransformation of anthocyanins are reviewed,which may provide useful reference for further research on the structural stability and physiological activity of anthocyanins and their broad application in pharmaceutical,food and cosmetic industries.

Key words: anthocyanins, biological activity, biotransformation, cell microbial transformation

ZHAO Xiang-jie, YANG Wen-jun, YANG Rong-ling, WU Ting-ting, WANG Zhao-yu, XU Ning-ning, HE Jia-mei. Research Progress on Biotransformation Modification of Anthocyanins[J]. Biotechnology Bulletin, 2019, 35(10): 205-211.

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