Advances in Mechanisms and Regulation of Iron Uptake and Metabolism in Rhizobia

doi:10.13560/j.cnki.biotech.bull.1985.2019-0767

Abstract

Abstract: Rhizobia are a collection of facultative symbiotic bacteria that possess the ability to establish symbiotic associations with legume hosts and carry out nitrogen fixation. Hence,they play important roles in the global nitrogen cycle and green sustainable agriculture. In order to adapt to the changing living environment such as soil,rhizosphere and infected host cells,it is vital for rhizobia to develop powerful strategies to sense and acquire nutrients. Iron is not only a limiting nutrient element for rhizobial growth and reproduction in the soil,but also directly involved in the synthesis of functional proteins closely related to symbiotic nitrogen fixation,such as nitrogenase,leghemoglobin and electronic respiratory chain components. Therefore,how rhizobia obtain iron under free-living and symbiotic conditions is highly concerned by scientists in the field of biological nitrogen fixation. Here we review recent researches on the uptake pathways of iron in different types such as Fe²⁺,Fe³⁺-siderophore complex,and heme and summarize regulation mechanisms of iron homeostasis mediated by RirA,Irr and other regulators in rhizobia,aiming to provide reference and insight for subsequent intensive researches.

Key words: rhizobia, iron uptake, siderophore, heme, iron homeostasis

JIAO Jian, LIU Ke-han, TIAN Chang-fu. Advances in Mechanisms and Regulation of Iron Uptake and Metabolism in Rhizobia[J]. Biotechnology Bulletin, 2019, 35(10): 7-17.

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