Small Non-coding RNA and Male Sterility

doi:10.13560/j.cnki.biotech.bull.1985.2016.01.007

Abstract

Abstract: Small non-coding RNA(sncRNA)is a kind of RNA with 20-30 nucleotides, and does not have the function of encoding proteins, but has extensive biological functions in terms of regulatory mechanism. In the process of animal sperm formation there are two types of sncRNAs, namely miRNAs and piRNAs playing a critical regulatory role. When they are expressed abnormally in testicular tissues of animals, which causes the production of sperms in obstacle, so as male sterility would appear. In this paper, we summarize sncRNA’s structure and function, and effects on male fertility in order to offer the references for the further researches of the sncRNA regulatory mechanisms.

Key words: small non-coding RNA, spermatogenesis, male sterility

LIAO Ke, CHAI Zhi-xin, ZHONG Jin-cheng. Small Non-coding RNA and Male Sterility[J]. Biotechnology Bulletin, 2016, 32(1): 33-40.

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