Abstract:

Weeds are one of the important adverse factors that seriously affect the yield and quality of crops, and weed control is an important aspect of field management. The ACCase is rate-limiting enzyme for fatty acids synthesis from acetyl-CoA, and ACCase-inhibitor herbicides inhibit ACCase activity, resulting in the obstruction of fatty acid synthesis and killing weeds. With the extensive application of herbicides in agricultural production, the issue of herbicide-resistant weeds has become increasingly serious, and the impact on crop yield and quality is particularly obvious. The development of elite herbicide-resistant germplasms and breeding new varieties with resistance to herbicide are effective strategies to control weeds in the field, especially for compound planting of mono-/dicotyledonous crops. The effective mutation sites were discovered in many crops and weeds through natural mutation, chemical mutagenesis, transgenic and gene editing techniques, and used in breeding applications. Here, we reviewed the properties and action mechanisms of ACCase in plants, the classification of ACCase-inhibitor herbicides, the resistant mechanism of ACCase, and their effective variations in crops. Finally, we proposed novel highly-effective breeding programs and strategies to improve high resistance to ACCase-inhibitor herbicides in crops.

Key words: ACCase, ACCase-inhibitor-like herbicide, compound planting, germplasm breeding