Classic Post-translational Modification in Ribosomally Synthesized and Post-translationally Modified Peptides Biosynthesis

doi:10.13560/j.cnki.biotech.bull.1985.2020-0136

Abstract

Abstract:

Ribosomally synthesized and post-translationally modified peptides（RiPPs）are a large class of natural products synthesized by ribosome via post-translational modification which feature a wide range of structural and biological diversity. We reviewed the various classes of RiPPs and their post-translationally modification mechanisms,discussed the significance of post-translational modifications,and prospected the development of RiPPs using genome mining under bioinformatics.

Key words: RiPPs, post-modification, biosynthetic pathway, genome mining

WANG Jin-xiu, ZHANG Qi, DING Wei, CHEN Tuo. Classic Post-translational Modification in Ribosomally Synthesized and Post-translationally Modified Peptides Biosynthesis[J]. Biotechnology Bulletin, 2020, 36(10): 215-225.

Figures/Tables 14

References 55

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