锌对哺乳动物细胞损伤的保护机制

摘要/Abstract

摘要： 锌是人体最重要的营养类微量元素之一，是细胞内许多酶类的辅因子和大分子物质的结构组成和活性中心。主要介绍锌在抗氧化，维持DNA 稳定和调控细胞凋亡方面的重要作用，综述锌对一些毒性物质，如重金属，过氧化氢，酒精等造成的细胞损伤的保护作用。

关键词: 锌, 氧化损伤, DNA 修复, 细胞凋亡

Abstract: Zinc is one of the most important nutritional trace elements of human body. It is essential to the structure and function of a large number of macromolecules and cofactor to more than 300 enzymes. We discussed the involvement of zinc in antioxidant defense, DNA integrity and apoptosis regulation, which protect cells against toxic substances, such as heavy metals, hydrogen peroxide and alcohol.

Key words: Zinc, Oxidative damage, DNA repair, Apoptosis

郑娟娟, 张雨, 许文涛, 黄昆仑. 锌对哺乳动物细胞损伤的保护机制[J]. 生物技术通报, 2013, 0(4): 21-26.

Zheng Juanjuan, Zhang Yu, Xu Wentao, Huang Kunlun. Overview of the Protection Effect of Zinc on Mammalian Cell Damage[J]. Biotechnology Bulletin, 2013, 0(4): 21-26.

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