生物技术通报 ›› 2020, Vol. 36 ›› Issue (12): 216-228.doi: 10.13560/j.cnki.biotech.bull.1985.2020-0365

• 综述与专论 • 上一篇    下一篇

蛋白源生物质的绿色生物转化

梁昕鑫1(), 唐丹1, 霍毅欣1,2()   

  1. 1.北京理工大学 生命学院 分子医学与生物诊疗工业和信息化部重点实验室,北京 100081
    2.苏州工业园区洛加大先进技术研究院,苏州 215123
  • 收稿日期:2020-04-01 出版日期:2020-12-26 发布日期:2020-12-22
  • 作者简介:梁昕鑫,女,硕士研究生,研究方向:酶工程;E-mail:xinxinliang111@126.com
  • 基金资助:
    国家自然科学基金项目(31961133014);中央高校基本科研业务费专项资金

Green Biotransformation of Protein-derived Biomass

LIANG Xin-xin1(), TANG Dan1, HUO Yi-xin1,2()   

  1. 1. Ministry of Industry and Information Technology Key Laboratory of Molecular Medicine and Biotherapy,School of Life Sciences,Beijing Institute of Technology,Beijing 100081
    2. SIP UCLA Institute for Technology Advancement,Suzhou 215123
  • Received:2020-04-01 Published:2020-12-26 Online:2020-12-22

摘要:

生物能源的大规模应用有助于环境保护和能源的可持续供给。目前生物燃料工艺开发实现了碳的循环利用,但尚未对氮的循环给予充分的重视。鉴于当前富含蛋白质的废弃物种类繁多且数量巨大,将蛋白质中氨基酸的碳骨架转化为生物燃料、大宗化学品及药物中间体等高附加值化合物正成为一个渐受关注的领域。从氨的生物循环利用角度入手,介绍了利用经光合作用生产的蛋白质等废弃物转化为高附加值化合物的高效、低成本、可持续的生产体系,并综述了进一步优化绿色转化技术所面临的挑战及可能的应对策略,旨为下一步高附加值化合物的低污染和高效生产提供参考。

关键词: 氮平衡, 蛋白源生物质, 生物转化, 高附加值化合物

Abstract:

The large-scale application of bioenergy contributes to environmental protection and sustainable energy supply. At present,the recycling of carbon in the development of biofuel technology has emerged,but the recycling of nitrogen has not been given sufficient attention. Considering the wide variety and huge amount of protein-rich wastes,the conversion of the carbon backbone of amino acids in proteins into high value-added compounds such as biofuels,bulk chemicals and pharmaceutical intermediates is becoming a growing concern. From the perspective of the biological recycling of ammonia,this paper details an efficient,low-cost and sustainable production system of converting protein-rich biomass waste produced by photosynthesis into high-value compounds. In addition,the paper also summarizes the challenges and feasible strategies in further optimizing the biotransformation technology,which provides a reference for the low pollution and efficient production of high value-added compounds in the next step.

Key words: nitrogen balance, protein-derived biomass, biotransformation, high value-added compounds