生物技术通报 ›› 2022, Vol. 38 ›› Issue (7): 13-22.doi: 10.13560/j.cnki.biotech.bull.1985.2022-0165

• 表观遗传学专题 • 上一篇    下一篇

植物组蛋白去甲基化酶研究进展

汤茜茜(), 林楚宇, 陶增()   

  1. 浙江大学农业与生物技术学院,杭州 310058
  • 收稿日期:2022-02-11 出版日期:2022-07-26 发布日期:2022-08-09
  • 作者简介:汤茜茜,女,硕士研究生,研究方向:分子植物病理学;E-mail: lilanniet@163.com
  • 基金资助:
    国家自然科学基金项目(31970534)

Research Progress in Histone Demethylase in Plant

TANG Qian-qian(), LIN Chu-yu, TAO Zeng()   

  1. College of Agriculture and Biotechnology,Zhejiang University,Hangzhou 310058
  • Received:2022-02-11 Published:2022-07-26 Online:2022-08-09

摘要:

组蛋白甲基化修饰在调控真核细胞的基因表达中起重要作用,组蛋白甲基化的水平受到组蛋白甲基转移酶(histone methyltransferases,HMTs)和组蛋白去甲基化酶(histone demethylases,HDMs)的动态调控,其中以在赖氨酸残基上的甲基化修饰最为常见。系统总结了植物组蛋白赖氨酸去甲基化酶的最新研究进展,阐述其在植物开花时间调控、昼夜节律调控等生长发育过程,以及植物对干旱、温度、病原菌等胁迫响应中的重要作用及其调控机制,为进一步利用植物组蛋白去甲基化酶在作物遗传改良中提供参考。

关键词: 组蛋白修饰, 组蛋白去甲基化酶, 生长发育, 胁迫响应

Abstract:

Histone methylation plays an important role in regulating gene expression in eukaryotic cells. Histone methylation is dynamically regulated by histone methyltransferases(HMTs)and demethylases(HDMs),among which methylation on lysine residues is the most common. In this paper,the latest research progress of plant histone lysine demethylase is systematically summarized,and its important role and regulation mechanism in the growth and development process of plant flowering time regulation and circadian rhythm regulation,as well as the responses of plants to drought,temperature,pathogenic bacteria and other stresses are expounded. The paper provides reference for further utilization of plant histone lysine demethylase in crop genetic improvement.

Key words: histone modification, histone lysine demethylases, growth and development, stress response