生物技术通报 ›› 2020, Vol. 36 ›› Issue (4): 159-163.doi: 10.13560/j.cnki.biotech.bull.1985.2019-0722

• 综述与专论 • 上一篇    下一篇

夏枯草多糖提取纯化及其药理作用研究进展

赵二劳, 刘乐, 范建凤, 赵三虎   

  1. 忻州师范学院化学系,忻州 034000
  • 收稿日期:2019-08-14 出版日期:2020-04-26 发布日期:2020-04-30
  • 作者简介:赵二劳,男,教授,研究方向:天然产物化学;E-mail:zel0350@163.com
  • 基金资助:
    山西省1331工程重点学科建设计划支持项目(2019),国家级大学生创新创业训练计划项目(201810124001),山西省高等学校大学生创新创业训练计划项目(2018507)

Research Progress on the Extraction,Purification and Pharmacological Effects of Polysaccharides from Prunella vulgarism

ZHAO Er-lao, LIU Le, FAN Jian-feng, ZHAO San-hu   

  1. Department of Chemistry,Xinzhou Teachers University,Xinzhou 034000
  • Received:2019-08-14 Published:2020-04-26 Online:2020-04-30

摘要: 夏枯草为临床常用中药,药理作用广泛,我国资源丰富。夏枯草含有三萜类、甾体类、黄酮类、香豆素类、有机酸和多糖等药效成分,其中多糖作为夏枯草主要药效成分之一,具有抗氧化、抗肿瘤、抗病毒和调节免疫功能等药理作用,有重要的临床应用和开发利用价值,在食品、医药、保健品等行业有诱人的应用前景。从提取、纯化和药理作用等方面梳理概述了国内夏枯草多糖研究进展,并展望了其研究方向,旨为夏枯草多糖的深入研究和临床应用提供参考。

关键词: 夏枯草, 多糖, 提取, 药理作用

Abstract: Prunella vulgaris is a clinically used Chinese medicine with extensive pharmacological effects,and it is abundant in China. P. vulgaris contains medicinal ingredients such as triterpenoids,steroids,flavonoids,coumarins,organic acids and polysaccharides. Polysaccharide is one of the main medicinal ingredients,and has pharmacological effects such as anti-oxidation,anti-tumor,anti-virus and immune regulation,thus it has important clinical application,development and utilization value,and has attractive application prospect in food,medicine,health care products and other industries. In this paper,the domestic research progresses on extraction,purification and pharmacological effect of polysaccharides from P. vulgarism are sorted,and its research direction is prospected,which provide references for the further research and clinical application of P. vulgarism polysaccharides.

Key words: Prunella vulgaris, polysaccharides, extraction, pharmacological effect