生物技术通报 ›› 2020, Vol. 36 ›› Issue (4): 185-191.doi: 10.13560/j.cnki.biotech.bull.1985.2019-0595

• 综述与专论 • 上一篇    下一篇

家禽卵泡闭锁机制的研究进展

邹坤, 路丽丽, Collins Asiamah Amponsah, 薛缘, 张少伟, 苏瑛, 赵志辉   

  1. 广东海洋大学农学院,湛江 524088
  • 收稿日期:2019-06-25 出版日期:2020-04-26 发布日期:2020-04-30
  • 作者简介:邹坤,男,硕士研究生,研究方向:动物遗传育种与繁殖;E-mail:xxxczk105@163.com
  • 基金资助:
    广东省科技厅科技计划项目(2017A020208066)

Research Progress on Mechanism of Poultry Follicular Atresia

ZOU Kun, LU Li-li, Collins Asiamah Amponsah, XUE Yuan, ZHANG Shao-wei, SU Ying, ZHAO Zhi-hui   

  1. Agricultural College,Guangdong Ocean University,Zhanjiang 524088
  • Received:2019-06-25 Published:2020-04-26 Online:2020-04-30

摘要: 家禽卵泡闭锁是一种受多种机制共同调控卵泡退化的过程,与家禽的繁殖性能密切相关。近年来,随着分子技术的快速发展,针对家禽卵泡细胞的凋亡和自噬引起卵泡闭锁的研究取得巨大进展。综述了家禽卵泡内细胞凋亡与自噬对家禽卵泡闭锁调控机制,讨论了卵泡细胞凋亡与自噬引起卵泡闭锁的意义及存在的问题。通过对家禽卵泡闭锁机制的研究,以期为家禽产蛋性能的充分利用和挖掘提供理论依据。

关键词: 家禽, 颗粒细胞, 凋亡, 自噬, 卵泡闭锁, 调控机制

Abstract: Poultry follicular atresia is a process that regulates follicular degeneration by a variety of mechanisms and is closely related to the reproductive performance of poultry. In recent years,with the rapid development of molecular technology,great progress has been made in the study of follicular atresia caused by apoptosis and autophagy in poultry follicular cells. In this paper,the regulation of apoptosis and autophagy for poultry follicular atresia in poultry follicles are reviewed. Then the significance and problems of follicular cell apoptosis and autophagy caused by follicular atresia are discussed. It provides a theoretical basis for the full utilization and excavation of poultry laying performance through the study of the mechanism of poultry follicle atresia.

Key words: poultry, granulosa cell, apoptosis, autophagy, follicular atresia, regulation mechanism