Biotechnology Bulletin ›› 2014, Vol. 0 ›› Issue (12): 24-28.doi: 10.13560/j.cnki.biotech.bull.1985.2014.12.004

• Review • Previous Articles     Next Articles

Progress on Oocytes Extracts-mediated Derivation of Pluripotent Stem Cells from Somatic Cells

Shen Xinyi, Song Kun, Yang Lishan, Xiao Xiong, Zhang Dapeng, Yang Bo, Li Yuemin   

  1. (Chongqing Key Lab of Forage & Herbivore, College of Animal Science and Technology, Southwest University, Chongqing 400715)
  • Received:2014-03-22 Online:2014-12-08 Published:2014-12-12

Abstract: Oocytes extracts-mediated derivation of pluripotent stem cells from somatic cells provides a new way for reprogramming. Morphologies, genes, and functions of somatic cells will be changed and somatic cells tend to be reprogrammed into stem cells after in-vitro co-incubation with oocytes extracts. The present situation, influence factors, existing problems, and prospects of somatic cells reprogramming using oocytes extracts were described in this review.

Key words: Oocytes, Oocytes extracts, Reprogramming, Somatic cells, Pluripotent stem cells