Biotechnology Bulletin ›› 2015, Vol. 31 ›› Issue (5): 41-47.doi: 10.13560/j.cnki.biotech.bull.1985.2015.05.007

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Research Progress on Methods of Removing Marker Genes in Transgenic Plants

Lang Yaoling1,2, Guan Xiaoyan1,2, Bai Guohui2, Liu Jianguo1,2   

  1. (1. School of Stomatology,Zunyi Medical University,Zunyi 563000; 2. Special Key Laboratory of Oral Diseases Research,Institutions of Higher Education in Guizhou Province,Zunyi 563000)
  • Received:2014-08-18 Online:2015-05-18 Published:2015-05-18

Abstract: With more and more varieties of transgenic plants emerging, environmental and food safety from using transgenic plants have been attracting extensive public attentions. One of the current problems is that the selectable marker genes, usually having the antibiotic or herbicide resistance, remain in transgenic plants. In order to improve the safety of using transgenic plants, removing marker genes from transgenic plants is not only conducive to the multiple using the same transgenic plants, but also more likely to allow the transgenic plants accepted by people. The current methods of removing marker genes in transgenic plants were reviewed, and the advantages and disadvantages of each method were compared from all aspects, which have a guiding significance for selecting a proper method in this field.

Key words: transgenic plants, selectable marker genes, safety