Research Progress on miR-143’s Biological Function

doi:10.13560/j.cnki.biotech.bull.1985.2016-1158

Abstract

Abstract: microRNAs are non-coding small RNAs with 21-25 nucleotides that ubiquitously are expressed in the eukaryote,and usually inhibit the expressions of its target genes at the post-transcriptional level. In recent years,miR-143 has been reported as canonical and multifunctional microRNA,which is widely expressed in various species. This paper reviews the biological functions of miR-143 such as cell proliferation,differentiation,apoptosis and tumorigenesis,aiming at providing a reference for relevant research.

Key words: miR-143, growth and development, disease

GAN Mai-lin, YANG Lu, TAN Ya, YANG Qiong, PU Hong-zhou, ZHANG Shun-hua, ZHU Li. Research Progress on miR-143’s Biological Function[J]. Biotechnology Bulletin, 2017, 33(6): 16-23.

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