Sulforaphane Nanoparticles and Biological Applications

doi:10.13560/j.cnki.biotech.bull.1985.2024-0554

Abstract

Abstract:

Sulforaphane is a phytochemical that has been reported to possess various biological activities such as antioxidant, anti-cancer, and anti-inflammatory. However, factors such as poor instability and thermal sensitivity of sulforaphane limit its application in different fields. Nanotechnology-based drug delivery systems offer the possibility of multidimensional applications of sulforaphane. By combining with nanotechnology, the bioavailability of sulforaphane can be improved and its clinical trials can be promoted. Based on the above characteristics, this paper presents a detailed overview of the specific mechanisms of action of different biological activities of sulforaphane, the characteristics of sulforaphane nanoparticles and their biological applications. Among them, it focuses on the overview of the characteristics of inorganic nanoparticles, organic nanoparticles and inorganic-organic composite nanoparticles applied for sulforaphane delivery, and summarizes the specific applications of sulforaphane nanoparticles according to their therapeutic diversity. In addition, the article gives an overview of the main issues and development prospects of sulforaphane nanoparticles, with a view to expanding the application fields of sulforaphane and injecting new impetus into the future development of food, health care, and medical science and technology.

Key words: sulforaphane, bioactivity, nanoparticle, drug delivery, targeted delivery

GAO Xin-ru, XU Wen-tao. Sulforaphane Nanoparticles and Biological Applications[J]. Biotechnology Bulletin, 2025, 41(1): 62-73.

Figures/Tables 2

References 92

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