生物质转化工程酿酒酵母的研究进展

doi:10.13560/j.cnki.biotech.bull.1985.2017.01.018

摘要/Abstract

摘要： 石油、煤炭等非再生资源的供给日益紧张，人类迫切需要对可再生资源的利用进一步开发。以生物质为原料生产纤维素乙醇具有原料可再生，成本低廉的显著优点。酿酒酵母菌株因其易于进行基因操作，并具有较高的抑制剂耐受性，被广泛用于发酵生产纤维素乙醇。酿酒酵母作为生物质转化工程菌，在如何提升菌株对抑制剂的耐受性和木糖转化效率等方面仍具有很大的挑战。综述了在生物质转化利用上酿酒酵母工程化的研究进展。

关键词: 酿酒酵母, 纤维素乙醇, 抑制剂耐受, 木糖利用, 基因工程

Abstract: With the increasing demand of oil,coal and other nonrenewable resources,it is urgent to develop the use of renewable and eco-friendly energy resources. The production of cellulosic ethanol from biomass has the advantage that the raw material is renewable and the cost is low. Saccharomyces cerevisiae has been most widely used for biomass conversion,with the characters of being easy for genetic engineering operation and high inhibitor tolerance. The two major challenges during the process of S. cerevisiae used for biomass conversion are the utilization of xylose and inhibitor tolerance. The major emphasis of this review will be the development of engineering Saccharomyces cerevisiae to improve inhibitor tolerance and speed up the transformation of xylose utilization.

Key words: Saccharomyces cerevisiae, cellulose ethanol, inhibitor tolerance, xylose utilization, genetic engineering

刘贺，朱家庆，纵秋瑾，李炳志，元英进. 生物质转化工程酿酒酵母的研究进展[J]. 生物技术通报, 2017, 33(1): 93-98.

LIU He, ZHU Jia-qing, ZONG Qiu-jin, LI Bing-zhi, YUAN Ying-jin. The Development of Engineered Saccharomyces cerevisiae for Biomass Conversion[J]. Biotechnology Bulletin, 2017, 33(1): 93-98.

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