植物iPGAM的研究进展

doi:10.13560/j.cnki.biotech.bull.1985.2015.09.001

摘要/Abstract

摘要： 辅因子非依赖型磷酸甘油酸变位酶(Cofactor-independent phosphoglycerate mutase，iPGAM)是在真菌和高等植物中发现的金属酶，是糖酵解和糖异生过程中的一个关键酶。随着原核生物、无脊椎动物等物种中iPGAM基因被克隆、蛋白晶体结构的解析及其生物学功能的陆续报道，近些年，植物iPGAM的功能开始受到关注。阐述了植物iPGAM蛋白的结构特点及作用机制，着重对已报道的拟南芥、水稻和玉米中iPGAMs的系统进化关系以及生物学功能进行了概述。

关键词: 植物, 辅因子非依赖型, 磷酸甘油酸变位酶

Abstract: Cofactor-independent phosphoglycerate mutase(iPGAM)is a metalloenzyme discovered in fungi and higher plants, i.e., a key enzyme in glycolysis and gluconeogenesis. With the progress on cloning of iPGAM gene, analysis of its protein crystal structure and biological functions in prokaryotes and invertebrates, the function of plant's iPGAM has captured the attentions. This article reviewed the structural characteristics, action mechanism of plant iPGAM proteins while emphatically introducing the phylogenetic relationships and biological functions of iPGAMs in Arabidopsis, rice and corn.

Key words: plant, cofactor-independent, phosphoglycerate mutase

谢鑫, 刘娜, 魏凤菊. 植物iPGAM的研究进展[J]. 生物技术通报, 2015, 31(9): 1-7.

Xie Xin, Liu Na, Wei Fengju. Research Progress on Cofactor-independent Phosphoglycerate Mutase in Plants[J]. Biotechnology Bulletin, 2015, 31(9): 1-7.

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