Biotechnology Bulletin ›› 2015, Vol. 31 ›› Issue (1): 67-72.doi: 10.13560/j.cnki.biotech.bull.1985.2015.01.010

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Advance Based on Signal Amplification Technology with Aptamer Biosensor

Xue Mingyue1,2, Qin Yingfeng, Li Jian, Ye Gaojie, Zhan Zhihua2   

  1. (1. Key Laboratory for the Chemistry and Molecular Engineering of Medical Resources(Ministry of Education of China),College of Chemistry and Pharmaceutical Sciences,Guangxi Normal Univeisitv,Guilin 541004;2. Guilin Normal College,Guilin 541001)
  • Received:2013-12-05 Online:2015-01-09 Published:2015-01-10

Abstract: Signal amplification technology has grown immensely in many fields because of its high accuracy and sensitivity at low concentrations. As a recognized molecule, aptamer has been used on many biosensors, and also has shown a good prospect in medical diagnosis, environmental monitoring and biological analysis. In recent years, biosensors with aptamer as recognized molecule has attracted more and more attention. The new research development of aptamer biosensors based on signal amplification technology in nearly three years was summarized especially.

Key words: signal amplification technology, aptamer, biosensor