Research Progress on Application of Ferritin Nanoparticles in the Field of Biomedicine

doi:10.13560/j.cnki.biotech.bull.1985.2015.10.010

Abstract

Abstract: Biological systems have generated wide varieties of nanoparticles during the process of long evolution. As one of naturally occurring nanoparticles, ferritin widely exists in all organisms, and is a key functional protein in life activities. Recently, the specific physicochemical properties of self-assembling ferritin nanoparticles allow it possessing the enormous advantages and application prospect in biomedical field. Current applications of ferritin nanocages include clinical measurements of trace amounts released into serum, nutritional sources of concentrated iron, nano biomaterial templates, and biological delivery of nanomaterials. This review presents an overview of ferritin nanoparticles in the diseases diagnose and treatment, delivery of medicines and development of vaccine, and outlines the potential prospects of applying ferritin nanoparticles on biomedicine.

Key words: ferritin, nanoparticles, biomedicine

Li Zhipeng, Liu Qingyou, Shi Deshun. Research Progress on Application of Ferritin Nanoparticles in the Field of Biomedicine[J]. Biotechnology Bulletin, 2015, 31(10): 38-47.

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