The Development of Engineered Saccharomyces cerevisiae for Biomass Conversion

doi:10.13560/j.cnki.biotech.bull.1985.2017.01.018

Abstract

Abstract: With the increasing demand of oil,coal and other nonrenewable resources,it is urgent to develop the use of renewable and eco-friendly energy resources. The production of cellulosic ethanol from biomass has the advantage that the raw material is renewable and the cost is low. Saccharomyces cerevisiae has been most widely used for biomass conversion,with the characters of being easy for genetic engineering operation and high inhibitor tolerance. The two major challenges during the process of S. cerevisiae used for biomass conversion are the utilization of xylose and inhibitor tolerance. The major emphasis of this review will be the development of engineering Saccharomyces cerevisiae to improve inhibitor tolerance and speed up the transformation of xylose utilization.

Key words: Saccharomyces cerevisiae, cellulose ethanol, inhibitor tolerance, xylose utilization, genetic engineering

LIU He, ZHU Jia-qing, ZONG Qiu-jin, LI Bing-zhi, YUAN Ying-jin. The Development of Engineered Saccharomyces cerevisiae for Biomass Conversion[J]. Biotechnology Bulletin, 2017, 33(1): 93-98.

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