Research Progress on Food Fraud Using Non-targeted Metabolomics Based on High-resolution Mass Spectrometry

doi:10.13560/j.cnki.biotech.bull.1985.2018-0632

Abstract

Abstract: Food fraud is a type of economically motivated adulteration（EMA）,one of the most important factors affecting and destroying food safety. With the rapid development of living conditions,people demand food with better quality,thus food fraud has been concerned seriously by the public. Targeted metabolomics techniques for quantitative detection of known target substances have been widely used in food inspection,and metabolomics technology has become an indispensable tool in food science research. Regarding food fraud occurring in recent years,another branch of metabolomics,based on high resolution mass spectrometry（HRMS）,non-targeted metabolomics（NTM）was gradually applied and has made great development in the identification of food fraud. Here we introduced the workflow of identifying food fraud using HRMS-based NTM and summarized the data-progressing methods. Then we made a sum on the relevant applications for identifying frauds in food species/varieties,origin and quality respectively. Finally,we analyzed the advantages and disadvantages of HRMS-based NTM in food inspection and prospected other research directions. It is aimed that this work summarizes and describes the most recent metabolomics results in food inspection.

Key words: high-resolution mass spectrometry（HRMS）, metabolomics, food fraud

LAI Bo-wen, LIU Bin, LIANG Yong-kang. Research Progress on Food Fraud Using Non-targeted Metabolomics Based on High-resolution Mass Spectrometry[J]. Biotechnology Bulletin, 2019, 35(2): 192-197.

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