Roles of Dof Transcription Factors in the Regulation of Plant

doi:10.13560/j.cnki.biotech.bull.1985.2018-1062

Abstract

Abstract: As a plant-specific transcription-factor,DNA binding with one finger（Dof）protein was firstly discovered in corn in 1993. Dof has only one conserved zinc finger domain containing 52 amino acids. In general,the zinc finger domain contains 4 conserved Cys residues and one Zn²⁺,and these two components are both indispensable for Dof protein. Cysteine mutation or the presence of a divalent ion chelating agent will affect the formation of the zinc finger structure,and then the Dof protein cannot bind to the target DNA,resulting in the loss of its activity. The Cys residue and Zn²⁺ form a CX2CX21CX2C motif by covalent binding of other amino acid residues,and this motif may specifically recognize AAAG（or CTTT）sequences in promoters,thus activating or inhibiting the expression of target genes. Besides,the C-terminal amino acid sequence of the Dof protein was volatile,which led to the evolutionarily diverse and functional diversity of Dof transcription factor. To date,the Dof transcription factor was reported to play an important role in many aspects of plant growth and development,such as seed germination,development of vascular,leaf polarity,development of flower and pollen,photoperiod reaction,metabolism of carbon and nitrogen,regulation of secondary metabolites,and stress responses. This review focuses on the structure,phylogenetic relationship,and motif composition and regulation metabolism of Dof transcription factors,aiming at providing a theoretical basis for the further study of Dof transcription factors.

Key words: Dof transcription factor, conserved domain of single zinc finger, evolutionary relationship, regulate and control, metabolism

GUO Yan-xiu, CHEN Jing, WANG Yan-fang, SUN Chun-yu, WANG Yi, ZHANG Mei-ping. Roles of Dof Transcription Factors in the Regulation of Plant[J]. Biotechnology Bulletin, 2019, 35(5): 146-156.

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