Advances in Biosensors Based on Platinum Nanoclusters

doi:10.13560/j.cnki.biotech.bull.1985.2021-0247

Abstract

Abstract:

In the past few decades,gold and silver nanoclusters（Au NCs and Ag NCs）have been extensively explored and used in industrial catalysis,optoelectronic devices,biological imaging,environmental testing,clinical diagnosis and treatment. However,as precious metal clusters,there is relatively little discussion about the biosensing application of platinum nanoclusters（Pt NCs）. Pt NCs are of excellent reactivity,optical properties,catalytic activity,electrical conductivity and biocompatibility,and has been proven to be used in biosensing and medical imaging. In view of the above-mentioned excellent performance,we summarized Pt NCs from the perspective of synthesis and unique properties,and outlined their biological applications in sensing and imaging.

Key words: platinum nanoclusters, fluorescence, catalysis, biosensors

WANG Peng-fei, YANG Min, ZHU Long-jiao, XU Wen-tao. Advances in Biosensors Based on Platinum Nanoclusters[J]. Biotechnology Bulletin, 2021, 37(12): 235-242.

Figures/Tables 1

References 52

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配体 Ligand	发射波长 Emission wavelength/nm	颜色 Colour	量子产率 Quantum yield/%	参考文献 Reference
BSA	350-500	蓝色	/	[11]
N,N-二甲基甲酰胺（DMF）	484、544	青色、绿色	/	[32]
PAMAM（G4-OH）	470、520	蓝色、绿色	18、28	[33-34]
聚乙烯亚胺（PEI）	465、530、560	蓝色、绿色、黄色	4、11、7	[31]
谷胱甘肽（GSH）	570	黄色	17	[35]
硫辛酸（LA）	680	红色	47	[36]
血红蛋白（HGB）	450、760	蓝色、红色	/	[37]

配体 Ligand	发射波长 Emission wavelength/nm	颜色 Colour	量子产率 Quantum yield/%	参考文献 Reference
BSA	350-500	蓝色	/	[11]
N,N-二甲基甲酰胺（DMF）	484、544	青色、绿色	/	[32]
PAMAM（G4-OH）	470、520	蓝色、绿色	18、28	[33-34]
聚乙烯亚胺（PEI）	465、530、560	蓝色、绿色、黄色	4、11、7	[31]
谷胱甘肽（GSH）	570	黄色	17	[35]
硫辛酸（LA）	680	红色	47	[36]
血红蛋白（HGB）	450、760	蓝色、红色	/	[37]