Insights into Toll-like Receptor from Marine Animals

Abstract

Abstract: Toll-like receptors are a family of the primitive pattern recognition receptors in innate immunity system, which attract theinterest of immunologists all the time. Animals from the most ancient metazoan phylum porifera to bony fish are considered to possess TLR genes.In this paper, we collect the latest data about TLR and signaling pathway molecules from different marine phyla, the mechanisms of domainshuffling and polymorphism of TLR, which will be useful for exploring the origin of vertebrate TLR and prevent marine animals from diseases.

Key words: TLR , Marine animal , Signaling pathway , Domain shuffling , Polymorphism

Sun Hongjuan, Zhou Zunchun, Cui Jun, Wang Xiuli. Insights into Toll-like Receptor from Marine Animals[J]. Biotechnology Bulletin, 2013, 0(1): 41-48.

References

[1] Kawai T, Akira S. The role of pattern-recognition receptors in innateimmunity ：update on Toll-like receptors[J]. Nat Immunol, 2010,11（5）：373-384.
[2] Huang SF, Yuan SC, Guo L, et al. Genomic analysis of the immunegene repertoire of amphioxus reveals extraordinary innate complexityand diversity[J]. Genome Res, 2008, 18（7）：1112-1126.
[3] Hibino T, Loza-Coll M, Messier C, et al. The immune gene repertoireencoded in the purple sea urchin genome[J]. Dev Bio, 2006, 300（1）：349-365.
[4] O’Neill LAJ, Bowie AG. The family of five ：TIR-domain-containingadaptors in Toll-like receptor signaling[J]. Nat Rev Immunol,2007, 7（5）：353-364.
[5] Lin Q, Li MC, Fang D, et al. The essential roles of Toll-like receptorsignaling pathways in sterile inflammatory diseases[J]. IntImmunopharmacol, 2011, 11（10）：1422-1432.
[6] Keogh B, Parker AE. Toll-like receptors as targets for immunedisorders[J]. Trends Pharmacol Sci, 2011, 32（7）：435-442.
[7] Nusslein-Volhard C, Lohs-Schardin M, Sander K, et al. A dorsoventralshift of embryonic primordia in a new maternal-effect mutantof Drosophila[J]. Nature, 1980, 283（5746）：474-476.
[8] Medzhitov R, Janeway Jr CA．Innate immunity：impact on the adaptiveimmune response[J]. Curr Opin Immunol, 1997, 9（1）：4-9.
[9] Coscia MR, Giacomelli S, Oreste U. Toll-like receptors ：an overviewfrom invertebrates to vertebrates[J]. ISJ, 2011, 8 ：210-226.
[10] Wilson HV. On some phenomena of coalescence and regenerationin sponges[J]. J Exp Zool, 1907, 5（2）：245-258.
[11] Wiens M, Korzhev M, Perovic-Ottstadt S, et al. Toll-like receptorsare part of the innate immune defense system of sponges（demospongiae：Porifera）[J]. Mol Biol Evol, 2007, 24（3）：792-804.
[12] Srivastava M, Simakov O, Chapman J, et al. The Amphimedonqueenslandica genome and the evolution of animal complexity[J].Nature, 2010, 466（7307）：720-726.
[13] Gauthier ME, Du PL, Degnan BM. The genome of the sponge2013年第1期47 孙红娟等：海洋动物Toll 样受体的研究进展Amphimedon queenslandica provides new perspectives into theorigin of Toll-like and interleukin 1 receptor pathways[J]. EvolDev, 2010, 12（5）：519-533.
[14] Miller DJ, Hemmrich G, Ball EE, et al. The innate immunerepertoire in Cnidaria - ancestral complexity and stochastic geneloss[J]. Genome Biol, 2007, 8（4）：R59.
[15] Bosch TCG, Augustin R, Anton-Erxleben F, et al. Uncoveringevolutionary history of innate immunity ：the simple metazoanHydra uses epithelial cells for host defence[J]. Dev CompImmunol, 2009, 33（4）：559-569.
[16] Shinzato C, Shoguchi E, Kawashima T, et al. Using the Acroporadigitifera genome to understand coral responses to environmentalchange[J]. Nature, 2011, 476（7360）：320-323.
[17] De Lorgeril J, Zenagui R, Rosa RD, et al. Whole transcriptomeprofiling of successful immune response to vibrio infections in theoyster Crassostrea gigas by digital gene expression analysis[J].PLoS ONE, 2011, 6（8）：e23142. doi ：10.1371/journal.pone.0023142.
[18] Hou R, Bao ZM, Wang S, et al. Transcriptome sequencing and denovo analysis for Yesso scallop（Patinopecten yessoensis）using454 GS FLX[J]. PLoS One, 2011, 6（6）：e21560. doi ：10.1371/journal.pone.0021560.
[19] Venier P, Varotto L, Rosani U, et al. Insights into the innate immunityof the Mediterranean mussel Mytilus galloprovincialis[J].BMC Genomics, 2011, 12 ：69.
[20] Philipp EER, Kraemer L, Melzner F, et al. Massively parallel RNAsequencing identifies a complex immune gene repertoire in thelophotrochozoan Mytilus edulis[J]. PLoS One, 2012, 7（3）：e33091. doi ：10.1371/journal.pone.0033091.
[21] Wang M, Yanga J, Zhoua Z, et al. A primitive Toll-like receptor signalingpathway in mollusk Zhikong scallop Chlamys farreri[J].Dev Comp Immunol, 2011a, 35（4）：511-520.
[22] Zhang LL, Li L, Zhang GF. A Crassostrea gigas Toll-like receptorand comparative analysis of TLR pathway in invertebrates[J].Fish Shellfish Immunol, 2011, 30（2）：653-660.
[23] Inamori K, Ariki S, Kawabata S. A Toll-like receptor in horseshoecrabs[J]. Immunol Rev, 2004, 198 ：106-115.
[24] Belinda LW, Wei WX, Hanh BT, et al. SARM ：a novel Toll-likereceptor is functionally conserved from arthropod to human[J].Mol Immunol, 2008, 45（6）：1732-1742.
[25] Wang PH, Liang JP, Gu ZH, et al. Molecular cloning, characterizationand expression analysis of two novel Tolls（LvToll2 and Lv-Toll3）and three putative Sp?tzle-like Toll ligands（LvSpz1-3）fromLitopenaeus vannamei[J]. Dev Comp Immunol, 2012, 36（2）：359-371.
[26] Arts JA, Cornelissen FH, Cijsouw T, et al. Molecular cloning andexpression of a Toll receptor in the giant tiger shrimp, Penaeusmonodon[J]. Fish Shellfish Immunol, 2007, 23（3）：504-513.
[27] Yang CJ, Zhang JQ, Li FH, et al. A Toll receptor from Chinese shrimpFenneropenaeus chinensis is responsive to Vibrio anguillaruminfection[J]. Fish Shellfish Immunol, 2008, 24（5）：564-574.
[28] Mekata T, Kono T, Yoshida T, et al. Identification of cDNA encodingToll receptor, MjToll gene from kuruma shrimp, Marsupenaeusjaponicus[J]. Fish Shellfish Immunol, 2008, 24（1）：122-133.
[29] Assavalapsakul W, Panyim S. Molecular cloning and tissuedistribution of the Toll receptor in the black tiger shrimp, Penaeusmonodon[J]. Genet Mol Res, 2012, 11（1）：484-493.
[30] Rast JP, Smith LC, Loza-Coll M, et al. Genomic insights into theimmune system of the sea urchin[J]. Science, 2006, 314（5801）：952-956.
[31] 杨爱馥, 周遵春, 孙大鹏, 等. 仿剌参铁蛋白ferritin 基因的序列分析及表达[J]. 水产学报, 2010, 6（34）：710-717.
[32] Yang AF, Zhou ZC, He CB, et al. Analysis of expressed sequencetags from body wall, intestine and respiratory tree of sea cucumber（Apostichopus japonicus）[J]. Aquaculture, 2009, 296 ：193-199.
[33] Yang AF, Zhou ZC, Dong Y, et al. Expression of immune-relatedgenes in embryos and larvae of sea cucumber Apostichopusjaponicus[J]. Fish Shellfish Immunol, 2010, 29 ：839-845.
[34] Zhou ZC, Sun DP, Yang AF, et al. Molecular characterizationand expression analysis of a complement component 3 in the seacucumber（Apostichopus japonicus）[J]. Fish Shellfish Immunol,2011 ； 31 ：540-547.
[35] Sun LN, Chen MY, Yang HS, et al. Large scale gene expressionprofiling during intestine and body wall regeneration in the seacucumber Apostichopus japonicus[J]. Comp Biochem Physiol,2011, 6（2）：195-205.
[36] Du HX, Bao ZM, Hou R, et al. Transcriptome sequencing andcharacterization for the sea cucumber Apostichopus japonicus（Selenka,1867）[J]. PLoS One, 2012, 7（3）：e33311. doi ：生物技术通报 Biotechnology Bulletin 2013年第1期4810.1371/journal.pone.0033311.
[37] Delsuc F, Brinkmann H, Chourrout D, et al. Tunicates and notcephalochordates are the closest living relatives of vertebrates[J].Nature, 2006, 439（7079）：965-968.
[38] Yuan SC, Huang SF, Zhang W, et al. An amphioxus TLR withdynamic embryonic expression pattern responses to pathogens andactivates NF-κB pathway via MyD88[J]. Mol Immunol, 2009, 46（11-12）：2348-2356.
[39] Yuan SC, Wu K, Yang MY, et al. Amphioxus SARM involvedin neural development may function as a suppressor of TLRsignaling[J]. J Immunol, 2010, 184（12）：6874-6881.
[40] Azumi K, Santis R, Tomaso A, et al. Genomic analysis of immunityin a Urochordate and the emergence of the vertebrate immunesystem："waiting for Godot"[J]. Immunogenetics, 2003, 55（8）：570-581.
[41] Sasaki N, Ogasawara M, Sekiguchi T, et al. Toll-like receptors of theascidian Ciona intestinalis. prototypes with hybrid functionalities ofvertebrate toll-like receptors[J]. Biol Chem, 2009, 284（40）：27336-27343.
[42] Ishii A, Matsuo A, Sawa H, et al. Lamprey TLRs with propertiesdistinct from those of the variable lymphocyte receptors[J]. JImmunol, 2007, 178（1）：397-406.
[43] Kasamatsu J, Oshiumi H, Matsumoto M, et al. Phylogenetic andexpression analysis of lamprey toll-like receptors[J]. Dev CompImmunol, 2010, 34（8）：855-865.
[44] Cateni C, Paulesu L, Bigliardi E, Hamlett WC. The interleukinI（IL-1）system in the uteroplacental complex of a cartilaginousfish, the smoothhound shark, Mustelus canis[J]. Reprod BiolEndncrinol, 2003, 1 ：25.
[45] Wu BJ, Xin B, Jin M, et al. Comparative and phylogeneticanalyses of three TIR domain-containing adaptors in metazoans ：implications for evolution of TLR signaling pathways[J]. DevComp Immunol, 2011, 35（7）：764-773.
[46] Jault C, Pichon L, Chluba J. Toll-like receptor gene family and TIRdomainadapters in Danio rerio[J]. Mol Immunol, 2004, 40（11）：759-771.
[47] Oshiumi H, Tsujita T, Shida K, et al. Prediction of the prototype ofthe human Toll-like receptor gene family from the pufferfish, Fugurubripes, genome[J]. Immunogenetics, 2003, 54（11）：791-800.
[48] Yniv P. Toll-like receptors in bony fish ：From genomics tofunction[J]. Dev Comp Immunol, 2011, 35（12）：1263-1272.
[49] Wu BJ, Huan TX, Gong J, et al. Domain combination of thevertebrate-like TLR gene family ：implications for their origin andevolution[J]. J Genet, 2011, 90（3）：401-408.
[50] Pancer Z, Cooper MD. The evolution of adaptive immunity[J].Annu Rev Immunol, 2006, 24 ：497-518.