Research Progress of Goat Genome and Genetic Variation Map

doi:10.13560/j.cnki.biotech.bull.1985.2019-0691

Abstract

Abstract: The development of high-throughput sequencing technology and bioinformatics has greatly promoted the research of goat molecular biology. With the continuous improvement of goat reference genome and the application of whole genome re-sequencing technology,a large number of genetic variation information has been found at the whole genome level（SNP,Indel and CNV）,which enriches the available molecular markers used in goat molecular population genetics research. This paper reviews the research and application progress of goat reference genome and whole genome variation map on goat,aiming at providing scientific basis and reference for further genetic basic research and genetic resource conservation and utilization of goat traits by using molecular genetic markers.

Key words: goat, reference genome, genetic variation, single nucleotide polymorphism, insertion and deletion, copy number variation

LI Xiao-kai, FAN Yi-xing, QIAO Xian, ZHANG Lei, WANG Feng-hong, WANG Zhi-ying, WANG Rui-jun, ZHANG Yan-jun, LIU Zhi-hong, WANG Zhi-xin, HE Li-bing, LI Jin-quan, SU Rui, ZHANG Jia-xin. Research Progress of Goat Genome and Genetic Variation Map[J]. Biotechnology Bulletin, 2020, 36(4): 175-184.

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