拟南芥转录激活因子AtWRI1研究进展

doi:10.13560/j.cnki.biotech.bull.1985.2016.06.004

摘要/Abstract

摘要： 油脂具有较高的经济价值，研究植物油脂合成的调控过程具有重要意义。转录激活因子WRI1在油脂合成调控中起关键作用。综述了AtWRI1的发现及其结构特征、表达模式、功能和调控机制。AtWRI属于AP2/EREPB家族中的AP2亚族，具有7个外显子，在植物各器官的不同发育时期均有表达，但在种子的油脂合成时期表达量最高。它与相应的顺式作用元件结合，能够转录激活糖酵解和脂肪酸合成相关基因的表达，从而促进油脂的合成。AtWRI1是AtLEC1和AtLEC2的下游基因；在CRL3-BPM复合体介导下，AtWRI1通过泛素-26S蛋白酶体途径降解。

关键词: 油脂合成, AtWRI1, 表达模式, 转录激活, 调控机制

Abstract: As lipid has high economic value，studying the regulation process in oil biosynthesis is of great significance. WRI1，a transcriptional activator，plays a key role in this process. This paper focuses on its identification and structural characteristics，expression pattern，function and the regulation mechanism of AtWRII. It belongs to AP2 subtribe of AP2/EREB family and has 7 exons. It expresses at different developmental stages of each organ，and the expressional level reaches the maximum at the oil synthesis stage of seeds. Through binding corresponding cis-function components，it activates the transcription of genes involving in glycolysis and fatty acid synthesis，and consequently promotes the oil synthesis. AtWRII is one of the downstream genes of AtLEC1 and AtLEC2. Mediated by CRL3-BPM complex，AtWRI1 is degraded via ubiquitin-26S proteasome pathway.

Key words: oil synthesis, AtWRI1, expression pattern, transcriptional activation, regulation mechanism

杨先友, 黄有军, 张通, 黄春颖. 拟南芥转录激活因子AtWRI1研究进展[J]. 生物技术通报, 2016, 32(6): 13-18.

YANG Xian-you, HUANG You-jun, ZHANG Tong, HUANG Chun-ying. Advances on Transcriptional Activator AtWRI1 of Arabidopsis[J]. Biotechnology Bulletin, 2016, 32(6): 13-18.

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