植物WRKY转录因子家族研究进展

doi:10.13560/j.cnki.biotech.bull.1985.2019-0626

摘要/Abstract

摘要： WRKY转录因子是植物中最大的转录调控因子家族之一,是调控植物许多生物过程信号网络的组成部分。WKRY转录因子具有多种生物学功能,在植物的生长发育和衰老、非生物和生物胁迫等过程中发挥着重要的作用。在DNA水平上,WRKY转录因子可与靶基因启动子中的W-box TTGAC（C/T）结合,通过自调节或交叉调节激活或抑制下游基因的表达调控其反应。在蛋白水平上,WRKY转录因子可以与多种蛋白相互作用,包括MAP激酶、组蛋白去乙酰化酶、抗性R蛋白、多种转录因子等,调节植物的生长发育或各种应激反应。对WRKY转录因子的结构特征、生物学功能、调控机制和网络等方面进行了综述,有助于更加全面了解其在植物中的作用。

关键词: WRKY转录因子, 结构特征, 生物学功能, 调控机制, 调控网络

Abstract: WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form an integral part of signaling webs that modulates many plant processes. WKRY transcription factors have a variety of biological functions and play an important role in plant growth,development and senescence,abiotic and biotic stress and so on. At DNA level,WRKY transcription factors can bind to W-box TTGAC（C/T）in the promoter of its target genes and activate or inhibit the expression of downstream genes to regulate their response by self-regulation or cross-regulation. At protein level,WRKY transcription factors can regulate plant growth and development or various stress responses by interacting with a variety of proteins,including MAP kinases,histone deacetylase,resistant R proteins,and a variety of transcription factors. This paper reviews the research progress on the structure,biological function,regulatory mechanism and network of WRKY transcription factors,which will help us to understand their roles in plants more comprehensively.

Key words: WRKY transcription factor, structural characteristics, biological function, regulatory mechanism, regulatory network

黄幸, 丁峰, 彭宏祥, 潘介春, 何新华, 徐炯志, 李琳. 植物WRKY转录因子家族研究进展[J]. 生物技术通报, 2019, 35(12): 129-143.

HUANG Xing, DING Feng, PENG Hong-xiang, PAN Jie-chun, HE Xin-hua, XU Jiong-zhi, LI Lin. Research Progress on Family of Plant WRKY Transcription Factors[J]. Biotechnology Bulletin, 2019, 35(12): 129-143.

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