生物技术通报 ›› 2020, Vol. 36 ›› Issue (2): 58-64.doi: 10.13560/j.cnki.biotech.bull.1985.2019-0826

• 消化道微生物专题 • 上一篇    下一篇

鱼虾肠道菌群代谢产物短链脂肪酸研究进展

刘宇1,4, 丁倩雯1, 冉超2, 杨雅麟2, 王安然1, 张洪玲1, 张进雄1, 李解1, Rolf Erik Olsen3, Einar Ringø3, 张震2, 周志刚1   

  1. 1. 中国-挪威鱼类消化道微生物联合实验室,北京 100081;
    2. 中国农业科学院饲料研究所 农业部饲料生物技术重点实验室,北京 100081;
    3. 挪威-中国鱼类消化道微生物联合实验室,特隆赫姆,挪威;
    4. 北京市畜牧业环境监测站,北京 102200
  • 收稿日期:2019-09-05 出版日期:2020-02-26 发布日期:2020-02-23
  • 作者简介:刘宇,硕士研究生,研究方向:水产动物营养与饲料科学;E-mail:1126972553@qq.com
  • 基金资助:

    国家自然科学基金项目(31802315,31672294,31760762,31702354)

Research Advances on Short-chain Fatty Acids of Metabolites of Gut Microbiota in Aquatic Animals

LIU Yu1,4, DING Qian-wen1, RAN Chao2, YANG Ya-lin2, WANG An-ran1, ZHANG Hong-ling1, ZHANG Jin-xiong1, LI Jie1, Rolf Erik OLSEN3, Einar RINGØ3, ZHANG Zhen2, ZHOU Zhi-gang1   

  1. 1. China-Norway Joint Lab on Fish Gut Microbiota,Beijing 100081;
    2. Key Laboratory for Feed Biotechnology of the Ministry of Agriculture,Chinese Academy of Agricultural Sciences,Beijing 100081;
    3. Norway-China Joint Lab on Fish Gut Microbiota,Trondheim,Norway;
    4. Beijing Monitoring Station for Animal Husbandry Environment,Beijing 102200
  • Received:2019-09-05 Published:2020-02-26 Online:2020-02-23

摘要:

短链脂肪酸(Short-chain fatty acids,SCFAs)是指碳链中碳原子数量小于6个的有机脂肪酸,主要由食物中不消化的碳水化合物在体内经厌氧菌酵解生成,主要包括乙酸、丙酸、丁酸等。随着消化道微生物研究的不断深入,肠道微生物代谢产物—短链脂肪酸也被报道出具有重要的生理功能。主要综述了短链脂肪酸在水产动物营养代谢和免疫抗病上的作用,并对水产动物短链脂肪酸的研究短板进行了展望,以期推进水产动物短链脂肪酸的研究进程及实际应用。

关键词: 短链脂肪酸, 消化道微生物, 调控

Abstract:

Short-chain fatty acids(SCFAs)refer to organic fatty acids with less than 6 carbon atoms in the carbon chain. They are mainly produced by anaerobic glycolysis of indigestible carbohydrates in food,mainly including acetate,propionate,butyrate,etc. With the deep research of microbial flora in the digestive tract,microbial metabolites,short-chain fatty acids,have also been reported to have important physiological functions. This paper mainly reviews the role of SCFAs in the nutritional metabolism and immune disease resistance of aquatic animals. Meanwhile,this review outlooks the weakness of researching SCFAs in aquatic animals,aiming to promote the research process and actual application of SCFAs in aquatic animals.

Key words: short chain fatty acids, gut microbiota, regulation