Research Progress on the Technology of Pig Somatic Cell Nuclear Transfer

doi:10.13560/j.cnki.biotech.bull.1985.2016.08.008

Abstract

Abstract: The technology of pig somatic cell nuclear transfer has been developed for more than ten years,with gradual improvement of the technology,the cloned piglets and genetically modified piglets were generated in many laboratories. Recently,several effective gene targeting and regulating tools have developed quickly,which provides technology basis for the establishment of genetic modified pig models and promotes the transition of the related researches from basic to application. In this paper,its development process and the optimization of key procedures were introduced. The technical advantage,its applications and significances in agriculture and biomedicine were summarized. Meanwhile existing issues and applying prospects were discussed.

Key words: somatic cell nuclear transfer, pig, genetically modified, transfer genetic

ZHANG Hong-yan, XIN Ji-ge. Research Progress on the Technology of Pig Somatic Cell Nuclear Transfer[J]. Biotechnology Bulletin, 2016, 32(8): 41-46.

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