Application of Zebrafish in Research of Transgenic Organisms

Abstract

Abstract: The recent explosion of transgenic zebrafish lines in the literature demonstrates the value of this model system for detailed in vivo analysis of gene regulation, development and differentiation and morphogenetic movements, as well as drug screening and environment monitoring. After an outline of the application and development history of vital models from Escherichia coli to Musmusculus, the superiority of zebrafish as a model organism will be emphasized. Then this article will review the development history of transgenic technology in zebrafish and the uses of transgenic zebrafish. And finally problems in future development of transgenic zebrafish will be presented.

Key words: Model organism, Zebrafish, Danio rerio, Transgenic animal, Application

Liu Lili, Wang Jian, Wu Wei, Wang Haisheng, Yan Yanchun. Application of Zebrafish in Research of Transgenic Organisms[J]. Biotechnology Bulletin, 2013, 0(2): 15-21.

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