Gene Silencing in Planarian

Abstract

Abstract: Planarians have powerful capability of regenerating complete organisms from tiny fragments of their bodies, it’s a classic experimental model for investigating metazoan and has been revitalized by the application of modern molecular biological approaches. Gene silencing, which means special gene not expressing in organisms by some exogenous or endogenous reason. At present, RNA interference is a potent means to induce gene silencing in planarian and could play an important role in developmental biology and molecular biology. Gene silence mediated by exogenous or endogenous factors in planarians were reviewed in this paper, which is helpful for understanding of the molecular mechanisms of regeneration in planarian.

Key words: Planarian, Gene silencing, RNA interference, microRNA piwiRNA silencing

Wu Xue, Yuan Jinduo, Zhao Nannan, Yang Guiwen, An Liguo. Gene Silencing in Planarian[J]. Biotechnology Bulletin, 2013, 0(3): 24-29.

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