Biotechnology Bulletin ›› 2018, Vol. 34 ›› Issue (9): 90-96.doi: 10.13560/j.cnki.biotech.bull.1985.2018-0452

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Research Progress on the Sensors of High Analytical Performance Based on the Graphene and Its Related Material

LEI Xin-you, ZUO Guo-fang, WANG Peng, ZHANG Jian-bin   

  1. 1. Provincial Key Laboratory for New Molecule Material Design and Function of Gansu Universities,Tianshui 741000;
    2. College of Chemical Engineering and Technology,Tianshui Normal University,Tianshui 741000
  • Received:2018-05-15 Online:2018-09-26 Published:2018-10-10

Abstract: Based on the excellent electrical conductivity,large specific surface area and fine biocompatibility of graphene and graphene-related materials,the constructed sensors from graphene exhibit better properties than that by other materials. The application of graphene in sensing field is generally conducted by functionalization. The combination of graphene with polymer or nanoparticles may significantly enhance the response of the sensor and improve the sensitivity of detection. This paper reviews the recent advances in the application of graphene and its related materials in the sensing fields such as clinical analysis,environmental monitoring and food safety control. When the sensors are based on the graphene oxide and its derivatives(containing oxygen groups)with fine water dispersibility and biocompatibility,larger specific surface,flexible surface modification,and simple preparation,and their analytical performances are comprehensively evaluated by the analysis data of sensitivity,detection limit,etc. At the same time,the research trends of novel sensing material graphene and its derivatives is prospected:Precisely controlling the size and shape of graphene monodisperse,studying the sensing mechanism of the reaction between graphene and analyte molecular electrode under catalytic action,and reducing the aggregation of graphene sheet and precisely controlling the microstructure of graphene-based sensing system. It is expected as such:Developing portable chip-based sensors with more powerful characteristics to achieve the multi-analysis of complex environmental samples in a shorter time,to further increase the detection sensitivity and selectivity,to enhance the stability and reusability of the sensors,and to overcome toxicity and biological intolerance.

Key words: graphene, nanocomposites, sensor, biosensors, analytical performance