脂肪酸标准物质的研究进展

doi:10.13560/j.cnki.biotech.bull.1985.2019-0995

摘要/Abstract

摘要： 脂肪酸是一类具有重要功能的生物分子,广泛存在于动植物体内,是人体的重要组成成分,与人体很多疾病的发生都息息相关。脂肪酸标准物质是脂肪酸检测结果准确与否的依据,世界各国都在积极研制,目前我国脂肪酸标准物质研制单位主要有国家粮食局科学研究院和中国计量科学研究院等。综述了国内外脂肪酸标准物质的现状,对比分析了国内外脂肪酸标准物质的种类、特性量值组成和定值方法等。国外脂肪酸标准物质一般含有多种特性组分,特性量值较多,国内脂肪酸标准物质一般仅针对脂肪酸测量研制,基体比较单一,特性组分较少,量值较少。

关键词: 脂肪酸, 标准物质, 定值技术

Abstract: Fatty acid is a kind of biomolecule with important functions. It can be founded in many animals and plants,and it is also an important component of the human body. Fatty acid is closely related to many diseases in human beings. Fatty acid standard reference materials are the basis for the accuracy of detecting fatty acid,and countries in all over the world are actively developing them. Currently,the institutes of studying fatty acid standard reference materials in China mainly are National Institute of Metrology of China and Academy of State Administration of Grain. In this paper,the current status of fatty acid standard reference materials at home and abroad is reviewed,and the characteristics,composition and determination methods of fatty acid standard reference materialsare compared and analyzed. Foreign fatty acid standard reference materials generally contain a variety of characteristic components with more characteristic values,while domestic fatty acid standard reference materials are generally only developed for the measurement of fatty acids in food.The matrix is relatively single,the characteristic component is less,and the quantity is less.

Key words: fatty acids, standard reference material, determination of fatty acids

韩璐, 盛灵慧, 高运华, 吴枭, 王志栋, 李保山. 脂肪酸标准物质的研究进展[J]. 生物技术通报, 2020, 36(5): 9-15.

HAN Lu, SHENG Ling-hui, GAO Yun-hua, WU Xiao, WANG Zhi-dong, LI Bao-shan. Research Progress on Fatty Acid Standard Reference Material[J]. Biotechnology Bulletin, 2020, 36(5): 9-15.

参考文献

[1] 周文斌, 吕春明, 张宁, 等. 脂肪酸检测方法的研究进展[J]. 中国现代应用药学, 2014, 31(2):246-252.
[2] Tang CH, Xu JX, Peng ZY.Recentstudyonnutrition and function of fatty acids[J]. China Oils Fats, 2000, 25(6):20-23.
[3] 李秀琴, 逯海, 李红梅, 等. 食品安全化学计量技术与标准物质发展[J]. 食品安全质量检测学报, 2018, 9(15):3892-3896.
[4] Robert K.Consultative committee for amount of substance:metrology in chemistry and biology(CCQM)[J]. J Chem Metrol, 2018, 12(1):1-16.
[5] 刘小珊, 赵秀举, 胡志雄. 高脂血症血清脂肪酸分析[J]. 武汉轻工大学学报, 2015, 34(3):26-30.
[6] 马晓丽, 田兰, 李琳琳, 等. 基于气相色谱的血清中游离脂肪酸代谢轮廓分析区分糖尿病与正常人[J]. 分析科学学报, 2013, 29(5):615-619.
[7] 国家标准物质资源共享平台[EB/OL]. (2018-10-01)[2018-10-15]. http://www. ncrm. org. cn.
[8] 韩永志. 中华人民共和国标准物质目录[M]. 北京:中国计量出版社, 2000.
[9] 郝希成, 汪丽萍, 张蕊, 等. 菜籽油脂肪酸成分标准物质的研制[J]. 中国油脂, 2011, 36(6):68-71.
[10] 汪丽萍, 郝希成, 张蕊, 等. 大豆油脂肪酸成分标准物质的研制[J]. 粮油食品科技, 2011, 19(6):16-18.
[11] 汪丽萍, 郝希成, 张蕊, 等. 玉米油脂肪酸成分标准物质的研制[J]. 谷物化学与品质分析, 2011, 40(1):41-44.
[12] 汪丽萍, 郝希成, 张蕊, 等. 葵花籽油脂肪酸成分标准物质的研制[J]. 粮油食品科技, 2011, 19(1):29-31.
[13] Takamitsu O, Takashi Y, YoshieA, et al. Development of apple certified reference material for quantification of organophosphorus and pyrethroidpesticides[J]. Food Chemistry, 2013, 13:1243-1249.
[14] Lane S, Michele S, Katherrine S, et al.Standard Reference Materials to support measurement of fatty acids[J]. Lipid Technology, 2010, 21(1):7-12.
[15] Long SE, Catron BL, Boggs AS, et al.Development of Standard Reference Materials to support assessment of iodine status for nutritional and public health purposes[J]. American Journal of Clinical Nutrition, 2016, 104(3):90.
[16] Welch MJ, Colbert JC, GillL M, et al. The certification of SRM 1546 - meat homogenate, a new reference material for nutrients in a high protein, high fat matrix[J]. Fresenius Journal of Analytical Chemistry, 2001, 370(1):42-47.
[17] Sharpless KE, Greenberg RR, Schantz MM, et al.Filling the AOAC triangle with food-matrix standard reference materials[J]. Analytical &Bioanalytical Chemistry, 2004, 378(5):1161-1167.
[18] Lane S, Micheles S, KatherrineS, et al. Standard Reference Materials to support measurement of fatty acids[J]. Lipid Technology, 2009, 21(1):7-12.
[19] Sharpless KE, Brown TJ, Nelson BC, et al.Value assignment of nutrient concentrations in standard reference material 2384 baking chocolate[J]. J Agric Food Chem, 2002, 50(24):7069-7075.
[20] Michele M, Schant Z, Mary B, et al.Development of saw palmetto(Serenoarepens)fruit and extract standard reference materials[J]. Anal Bioanal Chem, 2008, 92(2):427-438.
[21] Michele M, Schantz, Lane C, et al.Development of botanical and fish oil standard reference materials for fatty acids[J]. Anal BioanalChem, 2013, 405(17):4531-4538.
[22] Prosekov AY.Geoforum food security:The challenge of the present[J]. Geoforum, 2018(91):73-77.
[23] Robert K.Consultative committee for amount of substance:metrology in chemistry and biology(CCQM)[J]. J ChemMetrol, 2018, 12(1):1-16.
[24] Rick L, PaulFrederic J. Determination of arsenic in food and dietary supplement standard reference materials by neutron activation analysis[J]. Journal of Radioanalytical& Nuclear Chemistry, 2013, 297(3):365-370.
[25] Rimmer CA, Sharpless, KE, Wise SA. Standard reference materials for dietary supplement analysis[J]. Analytical &Bioanalytical Chemistry, 2013, 405(13):4337-4344.
[26] Joint Research Centre(JRC)of the European Commission[J]. International Journal of Life Cycle Assessment, 2003, 8(4):190.
[27] De Bièvre P, Kramer G, Verbruggen A, et al.What is new in certified reference materials and measurements at IRMM?[J]. Fresenius Journal of Analytical Chemistry, 1995, 352(1-2):11-13.
[28] 李攻科, 何小青, 张展霞. 微波消解同时衍生化GC-MS法测定血浆中脂肪酸的研究[J]. 分析测试学报, 2000, 19(1):16-18.
[29] Yamamoto K, Kinoshita A, Shibahara A.Gas chromatographic separation of fatty acid methyl esters on weakly polar capillary columns[J]. Journal of Chromatography A, 2008, 1182(1):132-135.
[30] Swapnil VS, Elena B, Xuewei Z, et al.Botanical oils enriched in n-6 and n-3 FADS2 products are equally effective in preventing atherosclerosis and fatty liver[J]. Journal of Lipid Research, 2015, 56(6):1191-1205.
[31] 国家质量技术监督局. GB/T 173771998 动植物油脂脂肪酸甲酯的气相色谱分析[S].
[32] 国家质量技术监督局. GB/T 173761998 动植物油脂脂肪酸甲酯制备[S].
[33] 杨明, 邵鹏, 赵建业, 等. GC-MS双内标法测定植物油中脂肪酸组成[J]. 分析实验室, 2018, 37(7):801-808.
[34] 付大友, 颜杰. 国内色谱法研究人体内脂肪酸的综述[J]. 四川轻化工学院学报, 2003, 16(3):46-49.
[35] Jianwei R .Total serum fatty acid analysis by GC-MS:Assay validation andserum sample stability[J]. Current Pharmaceutical Analysis, 2013, 9(4):331-339.
[36] James GB, Gajendra R, Martin S, et al.LC/ESI-MS/MS detection of FAs by charge reversal derivatization with more than four orders of magnitude improvement in sensitivity[J]Lipid Res, 2013, 54
(12):3523-3530.
[37] 唐传核, 徐建祥, 彭志英. 脂肪酸营养与功能的最新研究[J]. 中国油脂, 2000, 25(6):20-23.
[38] 王鹏, 淮东欣, 盖江涛. 植物油脂中脂肪酸成分改良的生物技术研究进展[J]. 中国油料作物学报, 2015(6):907-914.
[39] 蒲凤琳, 孙伟峰, 车振明. 功能性油脂研究与开发进展[J]. 粮食与油脂, 2016, 29(8):5-7.
[40] 李秀琴, 逯海, 李红梅, 等. 食品安全化学计量技术与标准物质发展[J]. 食品安全质量检测学报, 2018, 15(9):3892-3896.