• 综述与专论 • 下一篇
田瑞丰1,2, 杨韵龙1,2, 周升辉3, 刘荣志1,2, 刘录祥3, 莫广刚1,2(
)
收稿日期:2026-01-21
出版日期:2026-08-28
通讯作者:
莫广刚mgg555@126.com作者简介:第一联系人:同等贡献
TIAN Rui-feng1,2, YANG Yun-long1,2, ZHOU Sheng-hui3, LIU Rong-zhi1,2, LIU Lu-xiang3, MO Guang-gang1,2(
)
Received:2026-01-21
Published:2026-08-28
摘要:
生物育种是种业创新的核心,是保障国家粮食安全、提升农业核心竞争力的关键路径。近年来,全球进入育种4.0时代,大数据、人工智能与生物技术的深度融合,推动精准高效育种体系快速发展。我国在转基因、基因编辑、基因组选择、合成生物学等前沿技术及底层工具构建方面取得重要进展,部分成果已达到国际先进水平,为种业创新奠定了坚实基础。本文综述了国内外生物育种技术发展态势与我国取得的阶段性成果,客观评估当前存在的技术差距与发展瓶颈,并提出针对性发展建议。未来亟需加快前沿技术原创突破,完善标准化、模块化和智能化育种平台,构建科研与产业深度协同的“双轮驱动”体系,优化政策法规环境,推动成果高效转化与产业化发展,为加快建设现代种业体系、保障国家粮食安全提供科技支撑。
田瑞丰, 杨韵龙, 周升辉, 刘荣志, 刘录祥, 莫广刚. 我国生物育种技术的研究现状与发展策略[J]. 生物技术通报, doi: 10.13560/j.cnki.biotech.bull.1985.2026-0089.
TIAN Rui-feng, YANG Yun-long, ZHOU Sheng-hui, LIU Rong-zhi, LIU Lu-xiang, MO Guang-gang. Research Status and Development Strategies of Biological Breeding Technologies in China[J]. Biotechnology Bulletin, doi: 10.13560/j.cnki.biotech.bull.1985.2026-0089.
生物技术 Biotechnology | 创新点 Innovation points | 衍生产品 Derivative products |
|---|---|---|
转基因技术 Transgenic technology | (1)基因导入,改变遗传信息; (2)多基因叠加,实现多性状改良; (3)精确基因调控; (4)抗性基因的应用 | (1)抗虫转基因作物:抗虫水稻、抗虫玉米; (2)抗除草剂作物:耐除草剂大豆、玉米等; (3)抗病作物:抗真菌小麦、抗病毒番茄; (4)改良营养价值的作物:黄金大米 |
基因编辑技术 Genome editing technology | (1)精确修改基因; (2)高效编辑多个基因; (3)无外源DNA引入; (4)快速育种周期 | (1)基因编辑小麦:抗病、抗旱的小麦品种; (2)基因编辑水稻:提高抗逆性、改良稻米品质; (3)基因编辑猪:耐病、改良肉质; (4)基因编辑玉米:抗病虫害改良 |
单倍体技术 Haploid technology | (1)通过单倍体生成纯合基因型; (2)加速基因型筛选; (3)快速育种体系 | (1)单倍体小麦:加速纯合筛选; (2)单倍体水稻:提高产量与抗性; (3)单倍体玉米:加速选育周期; (4)大豆单倍体诱导系 |
合成生物学 Synthetic biology | (1)基因线路设计与合成; (2)生物系统重构,增强代谢产物合成能力 (3)合成生命体; (4)绿色化学与环保技术 | (1)合成生物柴油、胰岛素等; (2)高效吸收CO2或修复土壤的植物; (3)生物降解材料:如生物降解塑料; (4)绿色能源作物:可用于生物燃料原料供给的能源植物 |
表1 主要生物育种技术创新点及衍生产品概览
Table 1 Overview of key innovations and derived products in biological breeding technologies
生物技术 Biotechnology | 创新点 Innovation points | 衍生产品 Derivative products |
|---|---|---|
转基因技术 Transgenic technology | (1)基因导入,改变遗传信息; (2)多基因叠加,实现多性状改良; (3)精确基因调控; (4)抗性基因的应用 | (1)抗虫转基因作物:抗虫水稻、抗虫玉米; (2)抗除草剂作物:耐除草剂大豆、玉米等; (3)抗病作物:抗真菌小麦、抗病毒番茄; (4)改良营养价值的作物:黄金大米 |
基因编辑技术 Genome editing technology | (1)精确修改基因; (2)高效编辑多个基因; (3)无外源DNA引入; (4)快速育种周期 | (1)基因编辑小麦:抗病、抗旱的小麦品种; (2)基因编辑水稻:提高抗逆性、改良稻米品质; (3)基因编辑猪:耐病、改良肉质; (4)基因编辑玉米:抗病虫害改良 |
单倍体技术 Haploid technology | (1)通过单倍体生成纯合基因型; (2)加速基因型筛选; (3)快速育种体系 | (1)单倍体小麦:加速纯合筛选; (2)单倍体水稻:提高产量与抗性; (3)单倍体玉米:加速选育周期; (4)大豆单倍体诱导系 |
合成生物学 Synthetic biology | (1)基因线路设计与合成; (2)生物系统重构,增强代谢产物合成能力 (3)合成生命体; (4)绿色化学与环保技术 | (1)合成生物柴油、胰岛素等; (2)高效吸收CO2或修复土壤的植物; (3)生物降解材料:如生物降解塑料; (4)绿色能源作物:可用于生物燃料原料供给的能源植物 |
| [1] | 刘庆, 刘秀丽. 生育政策调整背景下2018-2100年中国人口规模与结构预测研究 [J]. 数学的实践与认识, 2018, 48(8): 180-188. |
| Liu Q, Liu XL. Forecasting on China’s population size and structure during 2018-2100 with the background of family planning policy adjustment [J]. Math Pract Theory, 2018, 48(8): 180-188. | |
| [2] | 张健. 中国重要农作物生物育种产业化应用的展望 [J]. 中国农业科技导报, 2022, 24(12): 15-24. |
| Zhang J. Prospects for commercialization of biotech breeding technology of important crops in China [J]. J Agric Sci Technol, 2022, 24(12): 15-24. | |
| [3] | Crossa J, Pérez-Rodríguez P, Cuevas J, et al. Genomic selection in plant breeding: methods, models, and perspectives [J]. Trends Plant Sci, 2017, 22(11): 961-975. |
| [4] | Araus JL, Cairns JE. Field high-throughput phenotyping: the new crop breeding frontier [J]. Trends Plant Sci, 2014, 19(1): 52-61. |
| [5] | Mus F, Crook MB, Garcia K, et al. Symbiotic nitrogen fixation and the challenges to its extension to nonlegumes [J]. Appl Environ Microbiol, 2016, 82(13): 3698-3710. |
| [6] | Zhang Y, Liang Z, Zong Y, et al. Efficient and transgene-free genome editing in wheat through transient expression of CRISPR/Cas9 DNA or RNA [J]. Nat Commun, 2016, 7: 12617. |
| [7] | Jiao YQ, Wang YH, Xue DW, et al. Regulation of OsSPL14 by OsmiR156 defines ideal plant architecture in rice [J]. Nat Genet, 2010, 42(6): 541-544. |
| [8] | Wang HW, Sun SL, Ge WY, et al. Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat [J]. Science, 2020, 368(6493): eaba5435. |
| [9] | Duan XY, Chen CL, Du C, et al. Homozygous editing of multiple genes for accelerated generation of xenotransplantation pigs [J]. Genome Res, 2025, 35(5): 1167-1178. |
| [10] | Varshney RK, Bohra A, Yu JM, et al. Designing future crops: genomics-assisted breeding comes of age [J]. Trends Plant Sci, 2021, 26(6): 631-649. |
| [11] | Fu JY, Zheng SZ, Fan LJ, et al. Breeding 5.0: Artificial intelligence (AI)-decoded germplasm for accelerated crop innovation [J]. J Integr Plant Biol, 2025: jipb.70008. |
| [12] | Abramson J, Adler J, Dunger J, et al. Accurate structure prediction of biomolecular interactions with AlphaFold 3 [J]. Nature, 2024, 630(8016): 493-500. |
| [13] | He KH, Yu TX, Gao S, et al. Leveraging automated machine learning for environmental data-driven genetic analysis and genomic prediction in maize hybrids [J]. Adv Sci, 2025, 12(17): 2412423. |
| [14] | Yang F, Kong HJ, Ying J, et al. SeedLLM·Rice: a large language model integrated with rice biological knowledge graph [J]. Mol Plant, 2025, 18(7): 1118-1129. |
| [15] | 齐世杰, 赵静娟, 郑怀国. 基于ESI的全球作物生物育种领域研究前沿分析 [J]. 江苏农业科学, 2021, 49(19): 9-19. |
| Qi SJ, Zhao JJ, Zheng HG. Research frontier analysis of global crop biological breeding based on ESI [J]. Jiangsu Agric Sci, 2021, 49(19): 9-19. | |
| [16] | Li M, Sun CJ, Xu NY, et al. De novo assembly of 20 chicken genomes reveals the undetectable phenomenon for thousands of core genes on microchromosomes and subtelomeric regions [J]. Mol Biol Evol, 2022, 39(4): msac066. |
| [17] | Guo DL, Li Y, Lu HY, et al. A pangenome reference of wild and cultivated rice [J]. Nature, 2025, 642(8068): 662-671. |
| [18] | Jiao CZ, Xie XM, Hao CY, et al. Pan-genome bridges wheat structural variations with habitat and breeding [J]. Nature, 2025, 637(8045): 384-393. |
| [19] | Li D, Wang YL, Yuan TT, et al. Pangenome and genome variation analyses of pigs unveil genomic facets for their adaptation and agronomic characteristics [J]. iMeta, 2024, 3(6): e257. |
| [20] | 赵越, 张石来, 胡建, 等. 利用分子标记辅助选择技术培育抗虫水稻品种的研究 [J]. 中国农业科技导报, 2016, 18(3): 25-31. |
| Zhao Y, Zhang SL, Hu J, et al. Insect-resistant rice cultivar breeding by marker-assisted selection [J]. J Agric Sci Technol, 2016, 18(3): 25-31. | |
| [21] | Li XY, Lang ZH, Zhang J, et al. Acquisition of insect-resistant transgenic maize harboring a truncated cry1Ah gene via Agrobacterium-mediated transformation [J]. J Integr Agric, 2014, 13(5): 937-944. |
| [22] | Wei T, Jiang LJ, You X, et al. Generation of herbicide-resistant soybean by base editing [J]. Biology, 2023, 12(5): 741. |
| [23] | Lin QP, Zong Y, Xue CX, et al. Prime genome editing in rice and wheat [J]. Nat Biotechnol, 2020, 38(5): 582-585. |
| [24] | He Y, Liao SY, Ren QR, et al. CRISPR-Cas12i confers efficient genome editing and gene regulation in plants [J]. Plant Physiol, 2025, 198(1): kiaf125. |
| [25] | Karvelis T, Druteika G, Bigelyte G, et al. Transposon-associated TnpB is a programmable RNA-guided DNA endonuclease [J]. Nature, 2021, 599(7886): 692-696. |
| [26] | Lou HC, Li SJ, Shi ZH, et al. Engineering source-sink relations by prime editing confers heat-stress resilience in tomato and rice [J]. Cell, 2025, 188(2): 530-549.e20. |
| [27] | Xie Y, Zhang TH, Yang MH, et al. Engineering crop flower morphology facilitates robotization of cross-pollination and speed breeding [J]. Cell, 2025, 188(21): 5809-5830.e27. |
| [28] | 谷晓峰,张立超,李慧慧, 等. 农业生物智能设计育种[J].中国农业科技导报(中英文),2025,27 (12):1-13. |
| Gu X F, Zhang L C, Li H H, et al. Agro-biological intelligent design breeding[J]. J of Agric Sci Technol, 2025, 27(12): 1-13. | |
| [29] | 林敏. 农业生物育种技术的发展历程及产业化对策 [J]. 生物技术进展, 2021, 11(4): 405-417. |
| Lin M. The development course and industrialization countermeasure of agricultural biological breeding technology [J]. Curr Biotechnol, 2021, 11(4): 405-417. | |
| [30] | Zilberzwige-Tal S, Altae-Tran H, Kannan S, et al. Reprogrammable RNA-targeting CRISPR systems evolved from RNA toxin-antitoxins [J]. Cell, 2025, 188(7): 1925-1940.e20. |
| [31] | Cong L, Ran FA, Cox D, et al. Multiplex genome engineering using CRISPR/cas systems [J]. Science, 2013, 339(6121): 819-823. |
| [32] | Zetsche B, Gootenberg JS, Abudayyeh OO, et al. Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-cas system [J]. Cell, 2015, 163(3): 759-771. |
| [33] | Jinek M, Chylinski K, Fonfara I, et al. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity [J]. Science, 2012, 337(6096): 816-821. |
| [34] | 徐以恒. “基因编辑农作物”专利规制的困境及出路 [J]. 中国农业科学, 2025, 58(5): 831-839. |
| Xu YH. The dilemma and way out of patent regulation for gene-edited crops [J]. Sci Agric Sin, 2025, 58(5): 831-839. | |
| [35] | Zhu WC, Li WF, Zhang HW, et al. Big data and artificial intelligence-aided crop breeding: Progress and prospects [J]. J Integr Plant Biol, 2025, 67(3): 722-739. |
| [36] | 刘海岚, 夏超, 兰海. 全基因组选择技术在作物育种中的研究进展 [J]. 华北农学报, 2022, 37(S1): 51-58. |
| Liu HL, Xia C, Lan H. The research progress of genomic selection in breeding of crops [J]. Acta Agric Boreali Sin, 2022, 37(S1): 51-58. | |
| [37] | 曹冰雪, 李鸿飞, 赵春江, 等. 智慧农业科技创新引领农业新质生产力发展路径 [J]. 智慧农业(中英文), 2024, 6(4): 116-127. |
| Cao BX, Li HF, Zhao CJ, et al. The path of smart agricultural technology innovation leading development of agricultural new quality productivity [J]. Smart Agric, 2024, 6(4): 116-127. | |
| [38] | 科学网. 孟山都推动农业数据科学平台转型 [N/OL]. 2017-09-20. |
| ScienceNet. Monsanto Promotes Transformation of Agricultural Data Science Platform [N/OL]. 2017-09-20. | |
| [39] | David E, Madec S, Sadeghi-Tehran P, et al. Global wheat head detection (GWHD) dataset: a large and diverse dataset of high-resolution RGB-labelled images to develop and benchmark wheat head detection methods [J]. Plant Phenomics, 2020, 2020: 3521852. |
| [40] | 张玉成, 张晓博, 高树琴, 等. “伏羲农场”: 智慧农业技术集成创新的实践探索与思考 [J]. 中国科学院院刊, 2025, 40(2): 301-309. |
| Zhang YC, Zhang XB, Gao SQ, et al. The Fuxi Farm: Practice and reflection on integrated innovation of smart agriculture technology [J]. Bull Chin Acad Sci, 2025, 40(2): 301-309. | |
| [41] | Ravari SZ, Dehghani H, Naghavi H. Assessment of salinity indices to identify Iranian wheat varieties using an artificial neural network: Assessment of salinity indices to identify Iranian wheat varieties [J]. Ann Appl Biol, 2016, 168(2): 185-194. |
| [42] | Demirci M, Gozde H, Taplamacioglu MC. Comparative dissolved gas analysis with machine learning and traditional methods [C]//2021 3rd International Congress on Human-Computer Interaction, Optimization and Robotic Applications (HORA). June 11-13, 2021. Ankara, Turkey. IEEE, 2021: 1-6. |
| [43] | 齐学礼, 陈艳艳, 王永霞, 等. 中国作物育种先进技术的研发现状与发展建议 [J/OL]. 分子植物育种, 2024. . |
| Qi XL, Chen YY, Wang YX, et al. Current status and development recommendations of advanced crop breeding technology in China [J/OL]. Mol Plant Breed, 2024. . | |
| [44] | 邢瑞淼, 闫文军, 魏玉君. 基于知识产权视角的中国种业政策分析 [J]. 西南大学学报(社会科学版), 2020, 46(1): 53-60, 194. |
| Xing RM, Yan WJ, Wei YJ. Analysis of China’s seed industry policy from the perspective of intellectual property [J]. J Southwest Univ Soc Sci Ed, 2020, 46(1): 53-60, 194. | |
| [45] | 裴瑞敏, 张超, 陈凯华, 等. 完善我国农作物种业国家创新体系促进创新链产业链深度融合 [J]. 中国科学院院刊, 2022, 37(7): 967-976. |
| Pei RM, Zhang C, Chen KH, et al. Promote deep integration of innovation chain and industry chain by improving national innovation systems of crop seed industry [J]. Bull Chin Acad Sci, 2022, 37(7): 967-976. | |
| [46] | 杨丽娟, 王士坤, 李洋, 等. 大数据背景下的信息化育种 [J]. 农学学报, 2021, 11(3): 55-59. |
| Yang LJ, Wang SK, Li Y, et al. IT application in breeding under the background of big data [J]. J Agric, 2021, 11(3): 55-59. | |
| [47] | 王述民, 李立会, 黎裕, 等. 中国粮食和农业植物遗传资源状况报告(Ⅱ) [J]. 植物遗传资源学报, 2011, 12(2): 167-177. |
| Wang SM, Li LH, Li Y, et al. Status of plant genetic resources for food and agricultural in China(Ⅱ) [J]. J Plant Genet Resour, 2011, 12(2): 167-177. | |
| [48] | 董玉琛. 我国作物种质资源研究的现状与展望 [J]. 中国农业科技导报, 1999, (2): 36-40. |
| Dong YC. Today and tomorrow of crop germplasm resources in China [J]. J Agric Sci Technol, 1999, (2): 36-40. | |
| [49] | 刘旭, 郑殿升, 董玉琛, 等. 中国农作物及其野生近缘植物多样性研究进展 [J]. 植物遗传资源学报, 2008, 9(4): 411-416. |
| Liu X, Zheng DS, Dong YC, et al. Diversity assessment of crops and their wild relatives in China [J]. J Plant Genet Resour, 2008, 9(4): 411-416. | |
| [50] | Rasheed A, Liu JD, Appels R, et al. Mobilizing Triticeae diversity from gene banks to farmer’s field [J]. Mol Plant, 2025, 18(4): 566-569. |
| [51] | Yang LB, He WC, Zhu YW, et al. GWAS meta-analysis using a graph-based pan-genome enhanced gene mining efficiency for agronomic traits in rice [J]. Nat Commun, 2025, 16: 3171. |
| [52] | Luo XM, Yang YM, Lin XL, et al. Deciphering spike architecture formation towards yield improvement in wheat [J]. J Genet Genom, 2023, 50(11): 835-845. |
| [53] | Li YH, Govta L, Sung YC, et al. The spectrum of diverse disease-resistance genes cloned and characterized in the triticeae tribe [J]. Annu Rev Phytopathol, 2025, 63: 175-200. |
| [54] | Chen BY, Wang CC, Zhuang YB, et al. Advances in understanding domestication-related genes for critical seed traits in soybean [J]. Seed Biology, 2026, 5(1):1-10. |
| [55] | 刘成, 韩冉, 汪晓璐, 等. 小麦远缘杂交现状、抗病基因转移及利用研究进展 [J]. 中国农业科学, 2020, 53(7): 1287-1308. |
| Liu C, Han R, Wang XL, et al. Research progress of wheat wild hybridization, disease resistance genes transfer and utilization [J]. Sci Agric Sin, 2020, 53(7): 1287-1308. | |
| [56] | Tian XB, Wang ZY, Liu WX, et al. Harness the wild: progress and perspectives in wheat genetic improvement [J]. J Genet Genom, 2026, 53(1): 1-15. |
| [57] | Tian ZX, Nepomuceno AL, Song QX, et al. Soybean2035: a decadal vision for soybean functional genomics and breeding [J]. Mol Plant, 2025, 18(2): 245-271. |
| [58] | 高建勋. 转基因作物产业化之风险预防研究 [J]. 中国社会科学院研究生院学报, 2018(5): 104-113. |
| Gao JX. On the risk precaution for the industrialization of GMOs [J]. J Graduate Sch Chin Acad Soc Sci, 2018(5): 104-113. | |
| [59] | 吴珊, 庞俊琴, 庄军红, 等. 我国转基因作物的研发与安全管理 [J]. 中国农业科技导报, 2020, 22(11): 11-16. |
| Wu S, Pang JQ, Zhuang JH, et al. Research, development, and safety administration of genetically modified crops in China [J]. J Agric Sci Technol, 2020, 22(11): 11-16. | |
| [60] | 王术坤, 韩磊. 中国种业发展形势与国际比较 [J]. 农业现代化研究, 2022, 43(5): 814-822. |
| Wang SK, Han L. Development situation and international comparison of China’s seed industry [J]. Res Agric Mod, 2022, 43(5): 814-822. | |
| [61] | 刘旭霞, 张楠. 中美转基因作物种植管理制度比较 [J]. 中国生物工程杂志, 2017, 37(8): 119-127. |
| Liu XX, Zhang N. Comparison of regulation on GM crops cultivation management in USA and China [J]. China Biotechnol, 2017, 37(8): 119-127. | |
| [62] | 马宇浩, 高爽, 董向会, 等. 基因编辑在农业动物中的应用进展 [J]. 农业生物技术学报, 2020, 28(12): 2230-2239. |
| Ma YH, Gao S, Dong XH, et al. Application progress of gene editing in agricultural animals [J]. J Agric Biotechnol, 2020, 28(12): 2230-2239. | |
| [63] | 张丽雯, 刘加兰, 王洪, 等. 基因编辑技术监管现状研究 [J]. 生命科学, 2022, 34(10): 1317-1326. |
| Zhang LW, Liu JL, Wang H, et al. Current supervision status of gene editing technology [J]. Chin Bull Life Sci, 2022, 34(10): 1317-1326. |
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