生物技术通报 ›› 2012, Vol. 0 ›› Issue (12): 19-24.

• 综述与专论 • 上一篇    下一篇

系统RNA干扰及在昆虫中的应用

王会冬, 龚亮, 胡美英, 洪鹏   

  1. 华南农业大学 天然源农药与化学生物学教育部重点实验室,广州 510642
  • 收稿日期:2012-05-16 修回日期:2013-01-25 出版日期:2012-12-26 发布日期:2013-02-06
  • 作者简介:王会冬, 男, 硕士研究生, 研究方向:昆虫分子生物学;E-mail:wowhd2011@163.com
  • 基金资助:
    : 国家自然科学基金项目(31171870)

Systemic RNA Interference and Its Application in Insect

Wang Huidong, Gong Liang, Hu Meiying, Hong Peng   

  1. Key Laboratory of Natural Pesticide and Chemical Biology,Ministry of Education,South China AgriculturalUniversity,Guangzhou 510642
  • Received:2012-05-16 Revised:2013-01-25 Published:2012-12-26 Online:2013-02-06

摘要: 系统性是RNA 干扰(RNA interference,RNAi)在植物和线虫中的一个重要特性,即RNAi 沉默信号可以在细胞和组织间进行传递,近年来研究发现某些昆虫中也存在系统RNAi 现象。RNAi 技术对很多领域的发展具有重要的促进作用,包括功能基因组学和害虫防治等领域。综述线虫,昆虫的系统性RNAi 研究概况以及RNAi 在昆虫领域的应用现状,并展望其应用前景。

关键词: RNA, 干扰, 系统性, sid-1, 昆虫

Abstract: A remarkable property of RNA interference(RNAi)in the nematode and plants is its systemic nature: silencing signals cancross cellular boundaries to silence gene expression distant from the site of initiation. In the past years,it is found that some insects can alsoshow systemic RNAi. RNAi technology has significant technological advances in diverse fields including functional genomics and agriculturalpest control. Here,we collected the current status of systemic RNAi in nematode and insects,we also introduce the current applications ininsects as well as expect its potential applications.